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The Karakalpak Autonomous Soviet Socialist Republic (Karakalpak ASSR; Karakalpak: Қарақалпақстан АССР; Uzbek: Қорақалпоғистон АССР; Russian: Каракалпакская АССР) was an autonomous republic of the Soviet Union. Until 20 July 1932, it was called the Karakalpak Autonomous Oblast. On 5 December 1936, it was merged with the Uzbek SSR. It was the only ASSR in Soviet Central Asia.
Its capital was Nukus (until 1939, Turtkul).
Today it corresponds to the autonomous republic of Karakalpakstan within Uzbekistan.