is the causative agent of infantile Leishmania infantum visceral leishmaniasis in the Mediterranean region of the [1 ] Old World and in Latin America, where it has been called Leishmania chagasi. [2 ] It is also an unusual cause of [3 ] cutaneous leishmaniasis, which is normally caused by specific lineages (or zymodemes). Wild [4 ] canids and domestic dogs are the natural reservoir of this organism. Leishmania infantum is closely related to , and some authors believe that these two species are so close as to actually be subspecies of each other; Leishmania donovani however, [5 ] phylogenetic analyses can easily distinguish between the two groups, although analysis has shown that some isolates of have been classified as Leishmania donovani Leishmania infantum and that the former includes a number of different genetic groups. [6 ]
References [ edit ]
^ Aoun, K.; Bouratbine, A. (2014). "Cutaneous Leishmaniasis in North Africa: a review.". Parasite 21: 14. doi: 10.1051/parasite/2014014. PMC 3952656. PMID 24626301.
^ Lukeš J. et al. (2007). "Evolutionary and geographical history of the . Leishmania donovani complex with a revision of current taxonomy" Proceedings of the National Academy of Sciences 104 (22): 9375–80. doi: 10.1073/pnas.0703678104. PMC 1890502. PMID 17517634.
^ Maurício IL, Stothard JR, Miles MA (May 2000). "The strange case of Leishmania chagasi". Parasitol. Today (Regul. Ed.) 16 (5): 188–9. doi: 10.1016/S0169-4758(00)01637-9. PMID 10782075.
^ BenSaid M, Guerbouj S, Saghrouni F, et al. (2006). "Occurrence of Leishmania infantum cutaneous leishmaniasis in central Tunisia". Transactions of the Royal Society of Tropical Medicine and Hygiene 100 (6): 521–26. doi: 10.1016/j.trstmh.2005.08.012. PMID 16356518.
^ Le Blancq SM, Peters W (1986). "Leishmania in the Old World: 4. The distribution of L. donovani sensu lato zymodemes". Trans. R. Soc. Trop. Med. Hyg. 80 (3): 367–77. doi: 10.1016/0035-9203(86)90320-2. PMID 3798531.
^ Kuhls K, Mauricio IL, Pratlong F, Presber W, Schönian G (2005). "Analysis of ribosomal DNA internal transcribed spacer sequences of the Leishmania donovani complex". Microbes Infect. 7 (11-12): 1224–34. doi: 10.1016/j.micinf.2005.04.009. PMID 16002315.
External links [ edit ]