Moore has been making music since he was 7 years old. He released his first single, "The Texas Twist" when he was 10 years old, which was #1 locally in Dallas for 6 straight weeks. When he was 12 years old, Lil Twist had his mom drive him an hour to a Lil Wayne concert in Tyler, Texas. He got to open for Lil Wayne after getting Lil Wayne's manager, Cortez Bryant to let him perform. Impressed, Cortez and Wayne flew Lil Twist to Atlanta to see how he was in a recording studio.
Lil Twist was signed to Young Money Records after Lil Wayne saw him perform at one of his concert openings in 2007. He released mixtapes such as The Golden Child, and a single, “Love Affair,“ to build anticipation for his upcoming album, Don’t Get It Twisted. Before starting his 8-month stint in prison, Lil Wayne gave Twist the nickname of "Twizzy F. Baby" (much like "Weezy F. Baby').