The right sympathetic chain and its connections with the thoracic, abdominal, and pelvic plexuses. (Greater and lesser splanchnic nerves labeled at left.)
Abdominal portion of the sympathetic trunk, with the celiac and hypogastric plexuses. (Greater splanchnic and lowest splanchnic labeled at upper left. Greater splanchnic and lesser splanchnic labeled at upper right.)
The nerve travels inferiorly, lateral to the greater splanchnic nerve. Its fibers synapse with their postganglionic counterparts in the superior mesenteric ganglia, or in the aorticorenal ganglion. The nerve modulates the activity of the enteric nervous system of the midgut.
The nerve's origins can be remembered by the "4-3-2 rule", accounting for the number of ganglia giving rise to each nerve. However, different sources define the nerves in different ways, so this rule may not always be reliable.