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| style="text-align:center; colspan=2 | <center><font size=4>'''Juice Plus</font></center>
| style="text-align:center; colspan=2 | <center><font size=4>'''Juice Plus</font></center>
[[Image:Juice Plus Orchard and Garden Blend.jpg|250px]]
[[Image:Juice Plus Orchard and Garden Blend.jpg|250px]]
<font size=3>'''Supplement Information</font>
{| width=100% cellpadding=0 cellspacing=1
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| bgcolor=black height=5 colspan=2 |
|-
| colspan=2 style="border-bottom:1px solid #555555" | <font size=2>'''Juice Plus Garden Blend*'''</font><br><font size=1>Serving Size = 2 capsules (1.5 g) </font><br>
{| width=100% cellpadding=0 cellspacing=1
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| bgcolor=black height=5 colspan=2 |
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| colspan=2 style="border-bottom:1px solid black" | <font size=1 face="verdana,arial">'''Amount per Serving'''</font>
{|
| ||||| <font size=1 face="verdana,arial">'''Amt'''</font>||||<font size=1 face="verdana,arial">'''% RDI'''</font>
|-
| Vitamin A||
|-
| (β-carotene)||||7000 IU ||||140%
|-
| Vitamin C|||| 42&nbsp;mg||||70%
|-
| Vitamin E|||| 24 IU||||80%
|-
| Folate|||| 0.28&nbsp;mg ||||70%
|-
| Calcium|||| 41&nbsp;mg ||||4%
|-
| Iron|||| 0.36&nbsp;mg ||||2%
|}
|-
| colspan=2 style="border-bottom:1px solid black" | <font size=1 face="verdana,arial">'''Ingredients'''</font>
Vegetable juice powder and pulp from carrots, parsley, beets, kale, broccoli, cabbage, spinach, and tomato; gelatin, lipase, amylase, protease, cellulase, beet fiber, barley bran, oat bran, cabbage fiber, [[glucomannan]], plant [[cellulose]], dried plant fiber, ''[[Lactobacillus acidophilus]]'', vegetable-derived [[magnesium stearate]], anthocyanins, allicin, lycopene, [[polyphenol]] catechins, ''[[Dunaliella salina]]'' (algae), and indole carbinols.
|-
| bgcolor=black height=5 colspan=2 |
|-
| colspan=2 style="border-bottom:1px solid #555555" | <font size=2>'''Juice Plus Orchard Blend*'''</font><br><font size=1>Serving Size = 2 capsules (1.5 g) </font><br>
|-
| bgcolor=black height=5 colspan=2 |
|-
{| width=100% cellpadding=0 cellspacing=1
| colspan=2 style="border-bottom:1px solid black" | <font size=1 face="verdana,arial">'''Amount per Serving'''</font>
{|
| ||||| <font size=1 face="verdana,arial">'''Amt'''</font>||||<font size=1 face="verdana,arial">'''% RDI'''</font>
|-
| Vitamin A||
|-
| (β-carotene)||||5,500 IU ||||110%
|-
| Vitamin C|||| 192&nbsp;mg||||320%
|-
| Vitamin E|||| 21 IU||||70%
|-
| Folate|||| 0.14&nbsp;mg ||||35%
|-
| Calcium|||| 20&nbsp;mg ||||2%
|-
| Iron|||| 0.36&nbsp;mg ||||2%
|}
|-
| colspan=2 style="border-bottom:1px solid black" | <font size=1 face="verdana,arial">'''Ingredients'''</font>
Fruit juice powder and pulp from apple, orange, pineapple, cranberry, peach, acerola cherry, and papaya; gelatin, bromelain, papain, lipase, amylase, protease, and cellulase; apple pectin, citrus pectin, date fiber, prune powder, glucomannan, citrus bioflavenoids, dried plant fiber, ''Lactobacillus acidophilus'', vegetable-derived magnesium stearate, anthocyanins, polyphenol catechins, ''Dunaliella salina'' (algae), and indole carbinols.
|-
| bgcolor=black height=5 colspan=2 |
|-

| colspan=2 | <small>*Percent RDI values as listed on bottle label; corresponding milligram amounts calculated based on USDA RDI guidleines for a 2,000 calorie diet. The manufacturer's suggested daily regimen is 2 Garden Blend capsules plus 2 Orchard Blend capsules per day (4 capsules total).
|}
|}
|}
|}
|}
'''Juice Plus+''' is a [[brand]]ed line of [[dietary supplement]]s containing concentrated [[fruit]] and [[vegetable]] juice extracts fortified with added vitamins and nutrients. It is produced by [[Natural Alternatives International]] of [[San Marcos, CA]] for [[National Safety Associates]] (NSA; [[Collierville, TN]]). Introduced in 1993,<ref name=mlmw2/> the supplements are distributed by NSA via [[multi-level marketing]].
'''Juice Plus+''' is a [[brand]]ed line of [[dietary supplement]]s containing concentrated [[fruit]] and [[vegetable]] juice extracts fortified with added vitamins and nutrients. It is produced by [[Natural Alternatives International]] of [[San Marcos, CA]] for [[National Safety Associates]] (NSA; [[Collierville, TN]]). Introduced in 1993,<ref name=mlmw2/> the supplements are distributed by NSA via [[multi-level marketing]].

Revision as of 21:20, 7 August 2011

[excessive citations]

Juice Plus

Supplement Information

Juice Plus Garden Blend*
Serving Size = 2 capsules (1.5 g)
Amount per Serving
Amt % RDI
Vitamin A
(β-carotene) 7000 IU 140%
Vitamin C 42 mg 70%
Vitamin E 24 IU 80%
Folate 0.28 mg 70%
Calcium 41 mg 4%
Iron 0.36 mg 2%
Ingredients

Vegetable juice powder and pulp from carrots, parsley, beets, kale, broccoli, cabbage, spinach, and tomato; gelatin, lipase, amylase, protease, cellulase, beet fiber, barley bran, oat bran, cabbage fiber, glucomannan, plant cellulose, dried plant fiber, Lactobacillus acidophilus, vegetable-derived magnesium stearate, anthocyanins, allicin, lycopene, polyphenol catechins, Dunaliella salina (algae), and indole carbinols.

Juice Plus Orchard Blend*
Serving Size = 2 capsules (1.5 g)
Amount per Serving
Amt % RDI
Vitamin A
(β-carotene) 5,500 IU 110%
Vitamin C 192 mg 320%
Vitamin E 21 IU 70%
Folate 0.14 mg 35%
Calcium 20 mg 2%
Iron 0.36 mg 2%
Ingredients

Fruit juice powder and pulp from apple, orange, pineapple, cranberry, peach, acerola cherry, and papaya; gelatin, bromelain, papain, lipase, amylase, protease, and cellulase; apple pectin, citrus pectin, date fiber, prune powder, glucomannan, citrus bioflavenoids, dried plant fiber, Lactobacillus acidophilus, vegetable-derived magnesium stearate, anthocyanins, polyphenol catechins, Dunaliella salina (algae), and indole carbinols.

*Percent RDI values as listed on bottle label; corresponding milligram amounts calculated based on USDA RDI guidleines for a 2,000 calorie diet. The manufacturer's suggested daily regimen is 2 Garden Blend capsules plus 2 Orchard Blend capsules per day (4 capsules total).

Juice Plus+ is a branded line of dietary supplements containing concentrated fruit and vegetable juice extracts fortified with added vitamins and nutrients. It is produced by Natural Alternatives International of San Marcos, CA for National Safety Associates (NSA; Collierville, TN). Introduced in 1993,[1] the supplements are distributed by NSA via multi-level marketing.

Studies of Juice Plus' effects have generated conflicting and controversial results. Although Juice Plus claims its products' efficacy is backed by research, critics have argued that there is no scientific proof that Juice Plus offers significant health benefits and that deceptive claims are used in the product's marketing information. Some marketing claims made about Juice Plus products have been disputed by consumer watchdog organizations and governmental agencies as misleading.[2]

History

Juice Plus was NSA's first nutritional product; since NSA was founded in 1970 it was known for other products such as water filters, air filters, fire-protection equipment, and educational games for pre-schoolers.,[3] which were also distributed by multi-level marketing. Naturopath Humbart "Smokey" Santillo is credited with having developed the Juice Plus concept and nutritional philosophy and for creating what has been described as the “original formula” for the product.[4][5][6] According to Santillo, he also worked with NSA to develop other Juice Plus products.[4]

The primary products in the Juice Plus line are "Orchard Blend" (a fruit juice powder-based vitamin supplement) and "Garden Blend" (vegetable juice powder-based) capsules, which are sold together in four-month supplies at a cost, in 2009, of approximately $167 USD. Other supplement products in the Juice Plus line include, or have included, Vineyard Blend (grape/berry juice powder-based) capsules, Juice Plus Complete (meal replacement powder), Juice Plus Gummies, Juice Plus Thins (wafers), chewable tablets,[7] and a vitamin formulation for dogs and cats.[8]

Manufacturing

The main ingredients in Juice Plus Orchard Blend and Garden Blend capsules (vegetable and fruit juices, fibers, plant enzymes, and food actives) are reduced to powder through a proprietary process by an unrelated supplier,[9] and then blended and encapsulated by NAI, who produce the finished product. Juice Plus capsules are “enriched with pure β-carotene, ascorbic acid, vitamin E, and folic acid”.[10] According to the manufacturer these are added to restore the levels of micronutrients lost during processing and to ensure uniformity.”[11] Two NAI-sponsored studies [12][13] mention that the fruit and vegetable powders in Juice Plus include standardized levels of natural β-carotene derived from Dunaliella salina and soy-derived d-α-tocopherol (vitamin E), which are supplied by the Henkel Corporation (now doing business as Cognis Corporation),[14][15] and ascorbic acid derived from acerola cherry, which is supplied by Schweizerhall Pharma.[16]

Sales

Juice Plus products are marketed by individual distributors who receive sales commissions ranging from 6% (for enrolling five customers in 30 days) to 14% (for enrolling twenty customers in 30 days).[17] Detailed sales figures for Juice Plus are not publicly available, but NSA representatives claimed that Juice Plus achieved monthly sales of $6 million USD in 1993[18] and that it was the company’s most successful new product.[19] According to NSA vice-president John Blair, sales of Juice Plus in 2008 were "approaching 300 million but have leveled off due to economic factors." [20]

Product research

Template:Unencyclopedic National Safety Associates, the owner of Juice Plus, claim that it is “the next best thing to eating fruits and vegetables”, containing the “nutritional essence of 17 different fruits, vegetables, and grains” with key phytonutrients and that the product is absorbed by the body, reduces oxidative stress, promotes cardiovascular wellness, supports a healthy immune system, and helps protect DNA.[21] Multiple studies have produced conflicting results as to the truth of these claims. Doubts have been raised about the advertised benefits of Juice Plus by Memorial Sloan-Kettering Cancer Center, University of California Berkeley, Center for Science in the Public Interest, and other sources.[1][6][10][22][23][24][25][26][27][28] The product has been criticized on the basis that: its marketing is unsupported by research data, it contains too little fruit and vegetable powder to offer significant clinical benefits,[22] its effects can be attributed to the inclusion of added exogenous vitamins and micronutrients, and it is excessively priced relative to its potential benefits.[1][6][23][25][26][29] Memorial Sloan-Kettering Cancer Clinic referred to Juice Plus as a “pricey supplement” that is “distributed through a multi-tiered marketing scheme with exaggerated value and cost." [6]

Of the published peer-reviewed studies on Juice Plus products, the majority were funded and/or authored by the manufacturer, Natural Alternatives International (NAI);[12][13][30][31][32][33][34] or the main distributor, NSA.;[31][35][36][37][38][39][40] two were funded by individual Juice Plus distributors;[41][42] and one was conducted independently.[43]

Nutrients and phytochemicals

Concerns have been raised that these nutrients in Juice Plus+ capsules may not be bioavailable, not effectively absorbed by the human body, and that some of the nutrients claimed to be in the products may not be present in significant amounts.[10] Studies on nutrient absorption showed that subjects taking Juice Plus had elevated blood levels of folate and β-carotene,[31][32][34][37] but the effects on blood levels of vitamin E and vitamin C were inconsistent. Some studies have shown significant increases in vitamin E[12][31][37] and C levels,[12][13][31][36] while other studies have shown much weaker effects on vitamin E[13][34] and C levels,[34] and that the levels of vitamin E are not significantly increased.[32][35] and vitamin C[32][35][37] Juice Plus was found to increase blood lycopene levels in several studies,[12][36][37] while other studies have indicated that Juice Plus does not raise blood levels of lycopene[32][34] or other phytochemicals in fresh fruits and vegetables such as lutein,[32][34][37] zeaxanthin,[32][34][36][37] and β-cryptoxanthin.[32][33][34][36][37]

Concerns have also been raised about the accuracy of product labeling. Three studies which included chemical analyses of Juice Plus have indicated nutrient amounts that differ from the amounts listed on the product labels.[30][44][45]

According to Consumer Reports, in 2005, National Safety Associates used advertising featuring Dr. William Sears (a distributor of Juice Plus products), which implied that Juice Plus Gummies are low in sugar and a nutritional alternative to fruits and vegetables. This claim resulted in consumer complaints to the Better Business Bureau's National Advertising Division (NAD). The BBB issued a complaint that NSA's claims were misleading, and as a result, NSA promised to modify its ads and stop calling Gummies “the next best thing to fruits and vegetables”.[2] However, the Juice Plus homepage continued to advertize the products as “the next best thing to fruits and vegetables”.[21]

In December 2007, the Center for Science in the Public Interest (CSPI) filed a complaint with the U.S. Food and Drug Administration (FDA) to “halt the marketing of NSA's Juice Plus Orchard Blend and Garden Blend capsules because the products appear to be adulterated and misbranded”.[46] CSPI said it was “concerned that the products' claim, ‘the next best thing to fruits and vegetables,’ may lead consumers to believe the pills are closer to real fruits and vegetables than is likely to be the case." According to CSPI, the labels say the capsules contain high levels of vitamins A and C and folate naturally, but “do not disclose that these vitamins and minerals are added to the capsules during processing and are nutrients only characteristic of the original fruit and vegetable sources.”

Registered dietician Fudeko T. Maruyama and nutritional education specialist Mary P. Clarke of Kansas State University commented that “the promotional literature for Juice Plus, billed as a whole food concentrate, is a carefully worded blend of incorrect information, misleading health claims, and nonscientific jargon” and concluded that “Juice Plus probably won't harm you, but can hurt your pocketbook."[26] Others have provided similar skeptical assessments of Juice Plus+.[2][22][24][25][29][47]

In November 2007, the Complaints Resolution Panel for the Therapeutic Goods Administration Advertising Code Council ruled that statements on NSA’s Juice Plus website were in breach of Australia’s Therapeutic Goods Advertising Code. According to the panel, the “clear message” in the ads was that Juice Plus tablets/capsules are “equivalent to fruits and vegetables” and that “consuming Juice Plus tablets would help Australians to consume the ‘recommended 5–7 servings’ of fruits and vegetables”. NSA was sanctioned by the Council to withdraw any representations that the products “are equivalent to fruits and vegetables or that their consumption can aid in meeting dietary recommendations relating to fruits and vegetables.” [48]

Antioxidant activity

NSA claims that Juice Plus is an effective antioxidant, and quotes a study that showed a 75% reduction in lipid peroxidation (an oxidative stress marker) in subjects that took Juice Plus for 7 to 28 days.[12] This report was criticized as “a particularly poor study” by nutritionist Rosemary Stanton[47] in the Australian journal, The Skeptic.[25]Other studies have also reported reductions in lipid peroxidation[13] and DNA oxidation.[32] These three studies were not blinded or placebo-controlled, included few participants (in one case no more than 15), and did not include monitoring or control of the participants' food intake. Other studies conducted under more rigorous conditions (randomized, double-blind, placebo-controlled, longer in duration and with more subjects), found no significant reductions in lipid peroxidation,[34][35][37] DNA oxidation,[31][35][36][37] or other markers of oxidative stress.[34][41]

One study, which measured in vitro antioxidant activity, found that 1 g of Juice Plus Orchard Blend/Garden Blend powder (500 mg of each combined) had the corresponding antioxidant capacity to approximately 10 g (fresh weight) of fruit or vegetable, amounting to 30 g (roughly one-third of a serving) per four capsules.[43] Tests of antioxidant activity of polyphenols (such as those in Juice Plus capsules) in vitro likely show higher results than the negligible antioxidant activity in vivo following oral ingestion and digestion.[49][50]

One placebo-controlled study conducted in 2002 found that Juice Plus Gummie candies did not significantly improve the antioxidant status of children, as indicated by negative results from 6 different antioxidant tests.[39] The authors explained this by saying it was possible that the supplement did not contain enough of the proper antioxidants to make a significant difference or that the antioxidants extracted in the fruit/vegetable extract were not bioavailable. The study was originally sponsored by NSA, but because the results were disappointing, NSA officials elected to remove the company’s name from the published article.[40]

Jim Sears, a pediatrician and Juice Plus distributor/spokesperson who co-hosts the syndicated daytime television talk show The Doctors, claimed on a February 27, 2009 episode of the program that Juice Plus “helps fight cancer”.[51] In October 2009, Dr. Barrie R. Cassileth, Chair and Chief of Integrative Medicine at Memorial Sloan-Kettering Cancer Center, cautioned that while Juice Plus is being “aggressively promoted to cancer patients based on claims of antioxidant effects”, the supplement should not be taken by patients because it can interfere with chemotherapy, nor should it be considered a substitute for fruits and vegetables.[52]

Cardiovascular system

Several studies have examined the effects of Juice Plus capsules on biochemical parameters associated with cardiovascular function, again with conflicting results. In October 2009, Dr. Barrie R. Cassileth, Chair and Chief of Integrative Medicine at Memorial Sloan-Kettering Cancer Center, noted that the results of Juice Plus studies on plasma homocysteine levels were not reproducible, and that studies on cardiovascular effects, such as blood pressure and cholesterol, were inconclusive.[52]

The effects of Juice Plus on blood levels of homocysteine have been reported in the following five studies all conducted in subjects with normal homocysteine levels (15 μmol/L).[53] An initial study, which was not double blinded or placebo controlled, reported a 37% decrease in homocysteine levels in subjects taking Juice Plus.[42] More rigorous studies, including three that were randomized, double-blind, placebo-controlled trials, found that homocysteine levels were not reduced[30][41] or were reduced to a much lesser extent than originally reported.[34][37]

Two randomized, double-blind placebo controlled studies have examined the effect of Juice Plus on serum cholesterol and LDL levels. One study found that Juice Plus had no significant effects;[34] the other found slight decreases in cholesterol (6%) and LDL (9%) in subjects that took Orchard/Garden Blend, but no reductions among subjects who took Juice Plus Vineyard blend in addition.[30]

A study reported that a combined regimen of Juice Plus Orchard Blend and Garden Blend significantly decreased the impairment of brachial artery vasoactivity caused by a high-fat meal in healthy subjects.[30] The addition of the Vineyard Blend product to this regimen had no additional effect on brachial artery vasoactivity and led to an increase in total lipoprotein and LDL as compared with Orchard Blend/Garden Blend alone.[54] This study also found that Juice Plus had no effect on blood pressure.

In a randomized placebo-controlled, crossover study in overweight insulin-resistant adults, 8-week supplementation with Juice Plus had no significant effect on vascular endothelial function, serum insulin, blood glucose, body weight, total cholesterol, or LDL cholesterol.[55][56]

Immune system

A non-randomized, non-blinded, non-controlled study in elderly cigarette smokers and non-smokers examined the effects of Juice Plus Orchard Blend and Garden Blend on 9 immunologic parameters, including stimulated T-cell cytokine production (IL-2, IL-6, TNF-α and IFN-γ) and the activity of various immune cells (peripheral blood monocytes, natural killer [NK] cells, T-helper cells, and cytotoxic T cells).[33] Juice Plus significantly increased peripheral blood monocyte proliferation and NK cell cytotoxicity in non-smokers but not in smokers, and increased in vitro IL-2 production by stimulated monocytes in both smokers and non-smokers. Juice Plus had no significant effect on cell counts (NK cells, T-helper cells, or cytotoxic T cells) or on the levels of IL-6, TNF-α, or IFN-γ in either smokers or non-smokers. Memorial Sloan-Kettering Cancer Center noted several faults with this study including that it lacked placebo controls and was not blinded, that the results do not necessarily correlate with an overall increase in immunity, and that it would have been more informative had clinical parameters been measured, such as whether fewer patients became sick.[6]

A double-blind, randomized, placebo-controlled study examined the effect of Juice Plus Orchard Blend and Garden Blend on T cell counts, lymphocyte cytokine production, Epstein-Barr virus (EBV) antibody titers, and the incidence of illness in healthy subjects.[36] The percentage of circulating γδ-CD3+ T cells and αβ-CD3+ T cells did not change significantly in subjects who took Juice Plus; however, at the end of the supplementation period, subjects taking the supplement had a significantly higher percentage of γδ-CD3+ T cells (7.2%) as compared with placebo (5.4%). IFN-γ produced by stimulated lymphocytes in vitro was reduced in the Juice Plus (68%) and placebo groups (41%), but the reduction was statistically significant only in the Juice Plus group. The levels of other cytokines (IL-4, IL-6, TGF-β) were unchanged and Juice Plus had no significant effect on the incidence and symptoms of illness or on EBV antibody titers.

A double-blind, randomized, placebo-controlled 28-week study examined the effect of Juice Plus (two capsules each of Orchard Blend, Garden Blend, and Vineyard blend per day) on cytokine (i.e., IL-6 and TNF-α) levels, and on the incidence of illness.[38] Subjects who took Juice Plus had lower TNF-α levels than the placebo group at later time points in the study (week 16 and 28) but overall the effect was not statistically significant.[38] Juice Plus was found to have no significant effect on IL-6 levels or on the incidence of illness during the course of the study.

Adverse effects

Adverse effects of Juice Plus have been mentioned in four studies,[13][33][57][58] none of which was randomized, blinded, or placebo-controlled. No monitoring of adverse effects was reported in other published Juice Plus studies.[12][30][31][32][34][35][36][41][42] Memorial Sloan-Kettering Cancer Center noted[6] that in one study,[33] some subjects who took Orchard Blend and Garden Blend developed a hive-like rash. Another study in 2000 reported adverse effects (upper-respiratory tract, urinary, and musculoskeletal) in roughly a third of the participants who took the products for 7 days. These events resolved spontaneously and were deemed unlikely to have derived from use of Juice Plus.[13] In a third study from 2007, some subjects withdrew due to gastrointestinal distress possibly caused by the Juice Plus regimen (a combination of Orchard Blend, Garden Blend, and Vineyard Blend).[57] Lastly, a medical case report was published in which Juice Plus was identified as the probable cause of liver toxicity (hepatic inflammation) in a 51-year old female patient with endometrial cancer. The liver injury was reversed upon discontinuation of Juice Plus.[58]

Conflicts of interest in studies

In a critique of Juice Plus,[1] consumer health advocate and alternative medicine critic Stephen Barrett of MLM Watch remarked upon the previous association between two authors of a 1996 Juice Plus research study [12] and United Sciences of America, Inc. (USAI), a multilevel marketing company that sold vitamin supplements with illegal claims that they could prevent many diseases.[59][60][61][62][63][64] In 1986, lead author John A. Wise, who later co-authored several other Juice Plus research studies,[30][31][32][33][37] was USAI's Executive Vice-President of Research and Development; and second author Robert J. Morin was a scientific advisor who helped design the products. State and federal enforcement actions[59][60][61][62][63][64] drove USAI out of business in 1987.[59][61][64] Wise became a consultant to Natural Alternatives International (NAI) in 1987 and a company executive (Vice-President of Research and Development) in 1992. Barrett noted that Wise was also an NAI shareholder and that production of Juice Plus for National Safety Associates (NSA) was responsible for 16% of NAIs sales in 1999.

NSAs Juice Plus website cites various research articles in support of the company's marketing claims about the biological effects of Juice Plus, maintaining that these “studies were conducted by independent researchers” at various universities.[65] Several of the studies were co-authored by Wise [12][30][32][33][37][66] and Morin.[12][66]

O.J. Simpson

University of California Berkeley Wellness Letter[22] and MLMWatch[1] also commented on the unreliability of Juice Plus testimonials provided by former professional athlete O.J. Simpson. Simpson, known commonly as "O.J." and "The Juice",[67] signed a multi-year six-figure contract with NSA in January 1994 and became an official celebrity endorser of Juice Plus. In March 1994, Simpson was videotaped telling 4,000 Juice Plus distributors at a sales meeting that the product had cured his arthritis, improved his golf game, and freed him from using anti-arthritic drugs.[1][68][69][70] However, regarding the murder of his ex-wife Nicole Brown Simpson and her friend, Ronald Goldman, for which Simpson was tried and acquitted, Simpson claimed in his defence that he was too incapacitated by arthritis to have committed the murders[22][1] and had continued to take the anti-inflammatory drug sulfasalazine.[71][1][72][73][74] As a result of the controversy surrounding Simpson, NSA cancelled his endorsement contract and stopped using the Simpson videotape to promote Juice Plus.[6][22]

Juice Plus Children's Research Foundation

The Juice Plus Children's Research Foundation (JPCRF),[75] founded in 1997, is a non-profit medical research organization (NTEE code H99)[76] whose stated goal is to initiate and/or support programs that advance the principle that improved nutrition leads to healthier lifestyle and overall better health in children. The foundation is chaired by executives of National Safety Associates and operates from the company's head office in Collierville, Tennessee. In fiscal year 2007, the majority of funds donated to the foundation were disbursed to Volunteers of America (a faith-based social welfare organization) and to the Boys and Girls Clubs of Memphis.[77]

The Foundation's website shows results of an ongoing customer survey (The Juice Plus Children's Health Study) which suggests a link between Juice Plus consumption and a general improvement in diet and lifestyle habits. The University of California Berkeley Wellness Letter and Stephen Barrett of MLM Watch questioned the survey's scientific value, and claimed that the Foundation is being used mainly as a marketing gimmick to get families to buy Juice Plus products.[23][78] Barrett's organization Quackwatch includes the JPCRF among its list of "Questionable 'Research' Entities".[79]

References

  1. ^ a b c d e f g h Barrett, Stephen. "Juice Plus: A Critical Look". MLM Watch. Retrieved 2009-08-21.
  2. ^ a b c "How Product Testimonials Bend The Rules". Consumer Reports. Archived from the original on 2006-07-21. Retrieved 2006-10-15. {{cite web}}: Cite has empty unknown parameter: |coauthors= (help); Italic or bold markup not allowed in: |publisher= (help) Cite error: The named reference "consumerreports" was defined multiple times with different content (see the help page).
  3. ^ "Marketing—education is NSA's new game". The Commercial Appeal. NewsLibrary.com. June 30, 1991.
  4. ^ a b "Smokey Santillo homepage". smokeysantillo.com. Retrieved 2007-09-15.[self-published source?]
  5. ^ [http://72.14.253.104/search?q=cache:vvwIAZDFON8J:www.nsa-convention.com/index.php%3Flang%3Den%26path%3Dfruehjahrs_convention/sprecher+%22juice+plus%22+santillo&hl=en&ct=clnk&cd=16&gl=us[dead link] "NSA Spring 2007 Convention speakers"]. nsa-convention.com. Retrieved 2007-09-15. {{cite web}}: Check |url= value (help)
  6. ^ a b c d e f g "Juice Plus". Memorial Sloan-Kettering Cancer Center. Archived from the original on 2008-03-08. Retrieved 2010-09-15.
  7. ^ "Other Juice Plus+® Products". juiceplus.com. Archived from the original on 2005-11-30. Retrieved 2011-06-01.
  8. ^ "Juice Plus+® for Dogs/Juice Plus+® for Cats" (PDF). nsaonline.com. Retrieved 2011-06-01.
  9. ^ "NSA International, Inc. Form 10-K (7/30/1996)". sec.edgar-online.com. Retrieved 2007-09-15.
  10. ^ a b c Watzl B, Bub A (November 2003). "Fruit and vegetable concentrate or vitamin supplement?". The Journal of Nutrition. 133 (11): 3725, author reply 3726. PMID 14608104.
  11. ^ Samman, S. (1 November 2003). "Letter to the Editor: Reply to Watzl and Bub" (pdf). J Nutr. 133 (7): 3726.
  12. ^ a b c d e f g h i j Wise JA, Morin RJ, Sanderson R, Blum K (1996). "Changes in plasma carotenoid, alpha-tocopherol, and lipid peroxide levels in response to supplementation with concentrated fruit and vegetable extracts: A pilot study". Curr Ther Res. 57 (6): 445–461. doi:10.1016/S0011-393X(96)80053-1.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  13. ^ a b c d e f g Leeds AR; et al. (2000). "Availability of micronutrients from dried, encapsulated fruit and vegetable preparations: a study in healthy volunteers". J Hum Nutr Diet. 13: 21–27. doi:10.1046/j.1365-277x.2000.00206.x. {{cite journal}}: Unknown parameter |author-separator= ignored (help)
  14. ^ [http://www.cognis.com/framescout.html?/nutritionandhealth/home.htm[dead link] "Cognis Nutrition and Health"]. cognis.com. Retrieved 2007-09-15. {{cite web}}: Check |url= value (help)
  15. ^ "Yahoo Finance: Cognis Corporation Company Profile". biz.yahoo.com. Retrieved 2007-09-16.
  16. ^ [http://www.schweizerhall.com/html/?id=100&L=1[dead link] "Schweizerhall Pharma homepage"]. schweizerhall.com. Retrieved 2007-09-15. {{cite web}}: Check |url= value (help)
  17. ^ "NSA Inc. Company Profile". biz.yahoo.com. Retrieved 2007-09-15.
  18. ^ Green, Frank (February 22, 1995). "O.J. plug is a plus. The prosecution mentions Juice Plus, and sales are up". San Diego Union-Tribune. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  19. ^ Riggs, Rod (June 19, 1993). "Olympics may mean gold for San Marcos firm". San Diego Union-Tribune.
  20. ^ "MLM company reports sales of Juice Plus+". NutritionalBusinessJournal.com. Retrieved 2009-05-01.
  21. ^ a b "Juice Plus homepage". National Safety Associates. Retrieved 2011-06-01.
  22. ^ a b c d e f "Juice Plus—and minus" (pdf). University of California Berkeley Wellness Letter. Retrieved 2006-10-15.
  23. ^ a b c "Juice Up and Dried Out". University of California Berkeley Wellness Letter. Archived from the original (pdf) on 2005-10-13. Retrieved 2009-21-15. {{cite web}}: Check |url= value (help); Check date values in: |accessdate= (help)
  24. ^ a b Goodwin, Kathy. "Dietary supplements: facts about Juice Plus". The Diet Channel. Retrieved 2006-10-15.
  25. ^ a b c d Stanton R (2000). "Nutrition: who can you believe?" (PDF). The Skeptic. 20 (4): 23–7. {{cite journal}}: External link in |author= (help)CS1 maint: numeric names: authors list (link)
  26. ^ a b c Maruyama, Fudeko T. (January 1995). "Juice Plus, Food or Supplement". Kansas State University, Dept. of Human Nutrition. Archived from the original on 2006-02-06. Retrieved 2007-07-22. {{cite web}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  27. ^ Schardt, David (December 2007). "Lost in translation: why real fruit and vegetables beat juices, powder, and purees" (pdf). Nutrition Action Healthletter. Center for Science in the Public Interest (CSPI). Retrieved 2008-03-11.
  28. ^ "The minuses of Juice Plus". Tufts University Health & Nutrition Letter. 24 (6): S1, 4. 2006. ISSN 1526-0143.
  29. ^ a b Schontz, Lori (January 15, 2007). "Nutritional shortcut bypasses benefits of eating the real thing". St. Louis Post-Dispatch. {{cite news}}: |access-date= requires |url= (help); Italic or bold markup not allowed in: |publisher= (help)
  30. ^ a b c d e f g h Plotnick GD, Corretti MC, Vogel RA, Hesslink R, Wise JA (May 2003). "Effect of supplemental phytonutrients on impairment of the flow-mediated brachial artery vasoactivity after a single high-fat meal". Journal of the American College of Cardiology. 41 (10): 1744–1749. doi:10.1016/S0735-1097(03)00302-4. PMID 12767658.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  31. ^ a b c d e f g h Kiefer I; Prock P; Lawrence C; et al. (June 2004). "Supplementation with mixed fruit and vegetable juice concentrates increased serum antioxidants and folate in healthy adults". Journal of the American College of Nutrition. 23 (3): 205–11. PMID 15190044. {{cite journal}}: Unknown parameter |author-separator= ignored (help)
  32. ^ a b c d e f g h i j k l Smith MJ, Inserra PF, Watson RR, Wise JA, O'Neill KL (1999). "Supplementation with fruit and vegetable extracts may decrease DNA damage in the peripheral lymphocytes of an elderly population". Nutr Res. 19 (10): 1507–1518. doi:10.1016/S0271-5317(99)00107-4.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  33. ^ a b c d e f g Inserra PF, Jiang S, Solkoff D, Lee J, Zhang Z, Xu M, Hesslink R, Wise J, Watson RR (1999). "Immune function in elderly smokers and nonsmokers improves during supplementation with fruit and vegetable extracts". Integr Med. 2 (1): 3–10. doi:10.1016/S1096-2190(99)00010-4.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  34. ^ a b c d e f g h i j k l m Samman S, Sivarajah G, Man JC, Ahmad ZI, Petocz P, Caterson ID (July 2003). "A mixed fruit and vegetable concentrate increases plasma antioxidant vitamins and folate and lowers plasma homocysteine in men". The Journal of Nutrition. 133 (7): 2188–93. PMID 12840177.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  35. ^ a b c d e f Bloomer RJ, Goldfarb AH, McKenzie MJ (June 2006). "Oxidative stress response to aerobic exercise: comparison of antioxidant supplements". Medicine and Science in Sports and Exercise. 38 (6): 1098–1105. doi:10.1249/01.mss.0000222839.51144.3e. PMID 16775552.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  36. ^ a b c d e f g h Nantz MP, Rowe CA, Nieves C, Percival SS (October 2006). "Immunity and antioxidant capacity in humans is enhanced by consumption of a dried, encapsulated fruit and vegetable juice concentrate". The Journal of Nutrition. 136 (10): 2606–10. PMID 16988134.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  37. ^ a b c d e f g h i j k l m Kawashima A, Madarame T, Koike H, Komatsu Y, Wise JA (2007). "Four week supplementation with mixed fruit and vegetable juice concentrates increased protective serum antioxidants and folate and decreased plasma homocysteine in Japanese subjects". Asia Pacific Journal of Clinical Nutrition. 16 (3): 411–21. PMID 17704021.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  38. ^ a b c Lamprecht M, Oettl K, Schwaberger G, Hofmann P, Greilberger JF (December 2007). "Several indicators of oxidative stress, immunity, and illness improved in trained men consuming an encapsulated juice powder concentrate for 28 weeks". The Journal of Nutrition. 137 (12): 2737–41. PMID 18029492.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  39. ^ a b Stewart, R.J. (2002). "Antioxidant status of young children: Response to an antioxidant supplement". J Am Diet Association. 102 (11): 1652–1657. doi:10.1016/S0002-8223(02)90352-4. {{cite journal}}: Invalid |display-authors=1 (help); Unknown parameter |month= ignored (help)
  40. ^ a b Canham M (2000). "U. Utah student uses gummy bears in research". Daily Utah Chronicle. High Beam Research. Retrieved 2007-09-15.
  41. ^ a b c d Bamonti F; et al. (2006). "Increased free malondialdehyde concentrations in smokers normalise with a mixed fruit and vegetable juice concentrate: a pilot study". Clin Chem Lab Med. 44 (4): 391–395. doi:10.1515/CCLM.2006.084. PMID 16599830. {{cite journal}}: Unknown parameter |author-separator= ignored (help)
  42. ^ a b c Panunzio MF (2003). "Supplementation with fruit and vegetable concentrate decreases plasma homocysteine levels in a dietary controlled trial". Nutr Res. 23 (9): 1221–1228. doi:10.1016/S0271-5317(03)00133-7. {{cite journal}}: Invalid |display-authors=1 (help); Unknown parameter |author-separator= ignored (help)
  43. ^ a b Chambers SJ (1996). "Evaluation of the antioxidant properties of a methanolic extract from 'Juice Plus fruit' and 'Juice Plus vegetable' (dietary supplements)". Food Chem. 57 (2): 271–274. doi:10.1016/0308-8146(95)00223-5. {{cite journal}}: Invalid |display-authors=1 (help); Unknown parameter |author-separator= ignored (help)
  44. ^ "EN Squeezes the Raw Truth Out of Juice Plus Claims". Environmental Nutrition. March 2002.
  45. ^ "Multivitamin/multimineral product review: ingredient comparison tables". Consumer Lab. 2006.
  46. ^ "CSPI targets juice capsules". The Tan Sheet. Vol. 15, no. 051. FDC Reports. December 17, 2007. {{cite news}}: |access-date= requires |url= (help); External link in |newspaper= (help)
  47. ^ a b [http://152.91.62.50/eventsdiary/ah04/speakers_rosemary_stanton.cfm[dead link] "Dr. Rosemary Stanton OAM"]. Australian Government; Australian Institute of Health and Welfare. Retrieved 2007-09-16. {{cite web}}: Check |url= value (help)
  48. ^ "Complaint 19-0607 Juice Plus (10/04/2007)". Complaints Resolution Panel; Therapeutic Goods Advertising Code Council. Archived from the original on 2009-02-04. Retrieved 2008-07-09.
  49. ^ Williams RJ, Spencer JP, Rice-Evans C (April 2004). "Flavonoids: antioxidants or signalling molecules?". Free Radical Biology & Medicine. 36 (7): 838–849. doi:10.1016/j.freeradbiomed.2004.01.001. PMID 15019969.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  50. ^ Frei, B. (April 1, 2009). "Controversy: What are the true biological functions of superfruit antioxidants?". Retrieved December 30, 2009. [dead link]
  51. ^ "[[The Doctors (2008 TV series)|The Doctors]] episode synopsis". February 27, 2009. Retrieved October 30, 2009. {{cite web}}: URL–wikilink conflict (help)
  52. ^ a b Cassileth B (2009). "Juice Plus". Oncology. 23 (11).
  53. ^ De Luca G, Suryapranata H, Gregorio G, Lange H, Chiariello M (November 2005). "Homocysteine and its effects on in-stent restenosis". Circulation. 112 (19): e307–11. doi:10.1161/CIRCULATIONAHA.105.573923. PMID 16275872.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  54. ^ Freedman JE (May 2003). "High-fat diets and cardiovascular disease: are nutritional supplements useful?". Journal of the American College of Cardiology. 41 (10): 1750–1752. doi:10.1016/S0735-1097(03)00303-6. PMID 12767659.
  55. ^ . The Yale-Griffin Prevention Research Center Newsflash. July, 2008 http://www.yalegriffinprc.org/downloads/newsflash/Newsflash_7.08.pdf. Retrieved 2009-03-31. {{cite news}}: Check date values in: |date= (help); Italic or bold markup not allowed in: |publisher= (help); Missing or empty |title= (help); line feed character in |publisher= at position 46 (help)
  56. ^ Kahn, Sam (November 29, 2004). "Pill may supplement fruits, vegetables". ”Yale Daily News”. Retrieved 2009-03-31.
  57. ^ a b Houston MC, Cooil B, Olafsson BJ, Raggi P. (2007). "Juice powder concentrate and systemic blood pressure, progression of coronary artery calcium and antioxidant status in hypertensive subjects: a pilot study" (pdf). ECAM. 4 (4): 455–462. doi:10.1093/ecam/nel108. PMC 2176151. PMID 18227913.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  58. ^ a b Naing A, Aaron J, Kurzrock R (2010). "Juice Plus or Toxicity Plus" (pdf). Am J Med. 123 (1): e1–e2. doi:10.1016/j.amjmed.2009.06.025. PMID 20102976.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  59. ^ a b c Barrett, Stephen. "The Rise and Fall of United Sciences of America". MLM Watch. Retrieved 2007-07-27.
  60. ^ a b Stare, F.J. (1986). "Marketing a nutritional "revolutionary breakthrough". Trading on names". N Engl J Med. 315 (15): 971–973. doi:10.1056/NEJM198610093151518. PMID 3762604. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  61. ^ a b c Young, E.A. (1987). "United Sciences of America, Incorporated: an "optimal" diet?". Ann Intern Med. 107 (1): 101–3. PMID 3592422. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  62. ^ a b Renner, J.H. (1986). "Science or scam?". N Engl J Med. 315 (15): 971–971. doi:10.1056/NEJM198610093151517. PMID 3762603. {{cite journal}}: Cite has empty unknown parameter: |coauthors= (help)
  63. ^ a b Holden, C. (1986). "Scientists get flak over marketing plan". Science. 234 (4780): 1063–1064. doi:10.1126/science.3775374. PMID 3775374. {{cite journal}}: Cite has empty unknown parameter: |coauthors= (help)
  64. ^ a b c "USA: The strange rise and fall of one MLM". Money (June 1). 1987. {{cite journal}}: Cite has empty unknown parameter: |coauthors= (help)
  65. ^ "Results of Juice Plus Clinical Research". National Safety Associates. Retrieved 2011-06-01.
  66. ^ a b Wise JA, Kaats GR, Preuss HG, Morin RJ. (2009). "β-Carotene and α-tocopherol in healthy overweight adults; depletion kinetics are correlated with adiposity". Int J Food Sci Nutr. 60 (s3): 65–75. doi:10.1080/09637480902852553.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  67. ^ University of Missouri-Kansas City School of Law: O.J.Simpson biography
  68. ^ Friedman, Roger (November 21, 2006). "If O.J. Simpson did it, this is how". Fox News. Retrieved 2007-09-15. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  69. ^ Deutsch, Linda (July 19, 1995). "Simpson exercise video shown in murder trial. Defendant jokes about punching wives". Fort Worth Star-Telegram. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  70. ^ "Simpson said capsules killed his arthritis pain". San Jose Mercury News. February 17, 1995. pp. 15A. Retrieved 2007-09-15. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  71. ^ Morrison, Patt (September 14, 2007). "Book review: After 'yuck,' the farce of O.J. Simpson's book -- 'If I Did It' reads like a self-absorbed counseling session". LA Times. Retrieved 2011-06-25. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  72. ^ Friedman, Roger (June 3, 2004). "O.J. defense doctor: 'some guilty people are set free'". Fox News. Retrieved 2007-09-15. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)
  73. ^ "Partial transcript of Simpson civil trial (Regina D. Chavez official reporter)". CNN. October 24, 1995. Retrieved 2007-09-15. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)[dead link]
  74. ^ "Simpson civil trial transcript (Regina D. Chavez official reporter)". CNN. January 6, 1997. Retrieved 2007-09-15. {{cite news}}: Italic or bold markup not allowed in: |publisher= (help)[dead link]
  75. ^ "Juice Plus Children's Research Foundation homepage". National Safety Associates. Retrieved 2006-10-15.
  76. ^ "Juice Plus Children's Research Foundation". Guidestar.org. Retrieved 2009-08-21.
  77. ^ pdf "IRS990 2008: Juice Plus Children's Research Foundation". United States Department of the Treasury Internal Revenue Service. February 6, 2009. Retrieved 2009-21-15. {{cite web}}: Check |url= value (help); Check date values in: |accessdate= (help) [dead link]
  78. ^ Barrett, Stephen. "Questionable Research by the Juice Plus Children's Research Foundation". MLM Watch. Retrieved 2007-02-05.
  79. ^ Barrett, Stephen. "Questionable Organizations: An Overview". QuackWatch. Retrieved 2009-09-21.
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