Terazosin: Difference between revisions
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'''Terazosin''' ('''Hytrin'''®) is a selective [[alpha 1 antagonist]] used for treatment of symptoms of [[prostate]] |
'''Terazosin''' ('''Hytrin'''®) is a selective [[alpha 1 antagonist]] used for treatment of symptoms of an enlarged [[prostate]] ([[benign prostatic hyperplasia|BPH]]). It also acts to lower the [[blood pressure]], and is therefor a drug of choice for men with [[hypertension]] and prostate enlargement. |
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It works by blocking the action of [[adrenaline]] on [[smooth muscle]] of the [[urinary bladder|bladder]] and the [[blood vessel]] walls. |
It works by blocking the action of [[adrenaline]] on [[smooth muscle]] of the [[urinary bladder|bladder]] and the [[blood vessel]] walls. |
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Revision as of 01:21, 19 November 2007
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| Clinical data | |
|---|---|
| ATC code | |
| Pharmacokinetic data | |
| Protein binding | 90-94% |
| Elimination half-life | 12 hours |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| DrugBank | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.118.191 |
| Chemical and physical data | |
| Formula | C19H25N5O4 |
| Molar mass | 387.433 g/mol g·mol−1 |
Terazosin (Hytrin®) is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefor a drug of choice for men with hypertension and prostate enlargement.
It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.
Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon.[1] Sexual side effects are rare, but may include priapism or erectile dysfunction.
Reference
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