|Systematic (IUPAC) name|
|Biological half-life||12 hours|
|CAS Registry Number|
|Molecular mass||387.433 g/mol|
|(what is this?)|
Terazosin (marketed as Hytrin or Zayasel) is a selective alpha 1 antagonist used for treatment of symptoms of an enlarged prostate (BPH). It also acts to lower the blood pressure, and is therefore a drug of choice for men with hypertension and prostate enlargement.
Most common side effects include dizziness, drowsiness, headache, constipation, loss of appetite, fatigue, nasal congestion or dry eyes, but they generally go away after only a few days of use. Therapy should always be started with a low dose to avoid first dose phenomenon. Sexual side effects are rare, but may include priapism or erectile dysfunction.
STARTING DOSAGE: The typical starting dose is 1mg by mouth each night before bed. It is not uncommon for this dosage to require a step-wise incremental increase over a period of several weeks to eventually reach an effective dose of 5mg or 10mg daily. Larger doses have not been demonstrated to be effective, though the trials evaluating this were not very extensive.
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