Talk:Celecoxib

what are the sexaul side effects of celebrex I am taking a single dose of 200 mg per day for suspected rheumatiod arthritis ----good or bad?

You'd notice, wouldn't you? JFW | T@lk 06:28, 14 July 2005 (UTC)

Celebrex off the market

I'm not prepared to do so, but I believe this article needs someone to edit it in regard to Celebrex being off the market in the USA. One FDA link is not gonna be enough. 68.104.201.53 05:15, 24 January 2006 (UTC)

Especially since I wouldn't want to be responsible for someone getting mistaken info off WP. 68.104.201.53

Or because it hasn't actually been withdrawn from the market? -Techelf 08:50, 24 January 2006 (UTC)

Not withdrawn, (the only COX-2 inhibitor not withdrawn?) but there is a current FDA alert: http://www.fda.gov/downloads/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124654.pdf.

Perhaps that should be more prominently displayed? Not because this is a medical reference web site, rather, because that is the single most interesting fact about the drug :~) —Preceding unsigned comment added by 218.214.18.240 (talk) 03:05, 4 November 2009 (UTC)

History section, as it was in the main article namespace.

==History== Apparently, Rochester claims that he should be entitled to the COX-2 patent (in a court claim).however, Pfizer took the patent because Rochester wasn’t able to prove evidence of written prescription requirements that will entitle him to the patent. [[User:Cutie sam|Cutie sam]] 04:44, 28 October 2006 (UTC)

• I'm not sure what to make of this. It seems unencyclopaedic/irrelevant, but maybe it isn't. It also has a signature in it - perhaps we should be clear that we'd like posts signed everywhere but the main namespace! -- (James McNally)  (talkpage)  10:32, 31 October 2006 (UTC)

A bit of illiteracy.

This paragraph, though expressive of information, should be edited into standard written English or excised: "It inhibit cyclo-oxygenase 2 only without affect cyclo-oxygenase 1 cox 1 inhibit prostaglandin and thromboxan but cox 2 inhibit prostaglandin only so inhibition of cox 2 only will inhibit PGs synthesis without affecting Thromboxan so it hasn't any effect on platlet aggregation or blood clotting" —Preceding unsigned comment added by 67.243.54.23 (talk) 19:43, 13 December 2008 (UTC)

Dr. Reuben

I wonder just how significant are Dr. Reuben's contributions to Celebrex research. Does the scandal merit inclusion in this article? There must be hundreds of researchers who publish articles about Celebrex. Why mention just one? Danglingdiagnosis (talk) 07:32, 24 March 2009 (UTC)

Is it just me or does this article seem as though it was written by some PR person from Phizer?

I mean, there is a lot of "this study's results may possibly suggest side effects if you believe it" type language instead of "this study demonstrated side effects which are commonly accepted to exist in the medical community." The tone of the side effects section seems very biased. —Preceding unsigned comment added by 24.9.53.25 (talk) 18:33, 4 April 2009 (UTC)

Has anyone heard about research suggesting that long term, high dosage use (400 mg's daily) of Celebrex actually causes arthritis? I read that NSAIDs like Celebrex work by reducing inflammation which is desirable. However, it might also block the synthesis of new cartilage in joints which will, over time, contribute to degeneration. So, if you only have osteoarthritis in your knee, for example, Celebrex might cause degenerative arthritis in all of your joints. I'm concerned about this research because 10 years ago, I was diagnosed with osteoarthritis (degenerative disc disease) in my lower back. Now, after taking maximum dose Celebrex with low dose Vicodin, I've been diagnosed with Fibromyalgia with constant, daily all-over pain. (69.109.156.184 (talk) 04:27, 23 September 2009 (UTC))

Hello I like to know something about this celebrex. I have been on this medcine and I was just told it has damaged my kidney's. I need answers. Please contact me. 832-397-9176 —Preceding unsigned comment added by 99.50.32.13 (talk) 22:03, 4 November 2009 (UTC)

Yep, the part about the study to "to establish more conclusively the true cardiovascular risk profile of celecoxib" feels entirely entered with bias by Pfizer or another stakeholder. I think it's the word "true" that gives away bias, like this study will put any fears to rest once and for all, and all other studies are less "true". I suggest removing this paragraph or rewriting it to be more neutral. --66.119.170.242 (talk) 21:06, 18 December 2009 (UTC)