Talk:Enobosarm: Difference between revisions
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To the editor that has been changing the article to say that the structure is incorrect, could you please detail your concerns here? It is preferable to discuss potential problems with the article here than in the text of the article itself. According to Chemical Abstracts, ostarine has the structure and data shown in the infobox, and it has the synonym S-4, and the CAS#401900-40-1 matches. It is certainly possible for multiple chemical databases to be incorrect, so could you point to a specific journal reference or something else in the primary literature that contradicts what is reported here or elsewhere? Thank you. -- [[User:Edgar181|Ed]] ([[User talk:Edgar181|Edgar181]]) 22:29, 19 November 2009 (UTC) |
To the editor that has been changing the article to say that the structure is incorrect, could you please detail your concerns here? It is preferable to discuss potential problems with the article here than in the text of the article itself. According to Chemical Abstracts, ostarine has the structure and data shown in the infobox, and it has the synonym S-4, and the CAS#401900-40-1 matches. It is certainly possible for multiple chemical databases to be incorrect, so could you point to a specific journal reference or something else in the primary literature that contradicts what is reported here or elsewhere? Thank you. -- [[User:Edgar181|Ed]] ([[User talk:Edgar181|Edgar181]]) 22:29, 19 November 2009 (UTC) |
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Thank you for the opportunity to clarify. True, the American Chemical Society formerly listed CAS#401900-40-1 as S-4 and Ostarine. This was a mistake on their part. |
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If you redo your search it is my understanding this has been corrected. They now correctly list S-4 as Andarine, which is the structe you show. Please note that S-1 is also not Ostarine. |
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If contact the American Chemical Society about this, you may get a reply such as "I am happy to report that the CAS record of interest has been corrected. Please accept our apology for any and all inconvenience." |
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According to GTx, the structure of Ostarine has never been officially released to the public. |
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Revision as of 01:30, 24 February 2010
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stereochemistry
Not sure about the stereochemistry around that chiral centre as different references show either enantiomer as the correct one! Currently going with the structure shown in Drug Discovery Today. 2007 March ; 12(5-6): 241–248 as this seems to be a fairly authoritative review on these compounds. Meodipt (talk) 00:11, 28 October 2008 (UTC)
- According to Chemical Abstracts, it is the S enantiomer which matches what is in the article now. -- Ed (Edgar181) 20:29, 29 October 2008 (UTC)
Correction needed?
To the editor that has been changing the article to say that the structure is incorrect, could you please detail your concerns here? It is preferable to discuss potential problems with the article here than in the text of the article itself. According to Chemical Abstracts, ostarine has the structure and data shown in the infobox, and it has the synonym S-4, and the CAS#401900-40-1 matches. It is certainly possible for multiple chemical databases to be incorrect, so could you point to a specific journal reference or something else in the primary literature that contradicts what is reported here or elsewhere? Thank you. -- Ed (Edgar181) 22:29, 19 November 2009 (UTC)
Thank you for the opportunity to clarify. True, the American Chemical Society formerly listed CAS#401900-40-1 as S-4 and Ostarine. This was a mistake on their part.
If you redo your search it is my understanding this has been corrected. They now correctly list S-4 as Andarine, which is the structe you show. Please note that S-1 is also not Ostarine.
If contact the American Chemical Society about this, you may get a reply such as "I am happy to report that the CAS record of interest has been corrected. Please accept our apology for any and all inconvenience."
According to GTx, the structure of Ostarine has never been officially released to the public.