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==Interactions==
==Interactions==
PPP4C has been shown to [[Protein-protein_interaction|interact]] with [[CCT2 (gene)|CCT2]],<ref name=pmid18715871>{{cite journal |last=Chen |first=Ginny I |coauthors=Tisayakorn Sally, Jorgensen Claus, D'Ambrosio Lisa M, Goudreault Marilyn, Gingras Anne-Claude |year=2008 |month=October |title=PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4 |journal=J. Biol. Chem. |volume=283 |issue=43 |pages=29273–84 |location = United States| issn = 0021-9258| pmid = 18715871 |doi = 10.1074/jbc.M803443200 |pmc=2662017 }}</ref><ref name=pmid16085932>{{cite journal |last=Gingras |first=Anne-Claude |coauthors=Caballero Michael, Zarske Marcel, Sanchez Amy, Hazbun Tony R, Fields Stanley, Sonenberg Nahum, Hafen Ernst, Raught Brian, Aebersold Ruedi |year=2005 |month=November |title=A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity |journal=Mol. Cell Proteomics |volume=4 |issue=11 |pages=1725–40 |location = United States| issn = 1535-9476| pmid = 16085932 |doi = 10.1074/mcp.M500231-MCP200 }}</ref> [[CCT4]],<ref name=pmid18715871/><ref name=pmid16085932/> [[CCT7]],<ref name=pmid18715871/><ref name=pmid16085932/> [[SMEK2]],<ref name=pmid17353931>{{cite journal |last=Ewing |first=Rob M |coauthors=Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel |year=2007 |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |pages=89 |location = England| issn = | pmid = 17353931 |doi = 10.1038/msb4100134 |pmc=1847948 |issue=1}}</ref><ref name=pmid18715871/><ref name=pmid16085932/> [[CCT6A]],<ref name=pmid18715871/><ref name=pmid16085932/> [[CCT3]],<ref name=pmid18715871/><ref name=pmid16085932/> [[IGBP1]],<ref name=pmid18715871/><ref name=pmid16085932/><ref name=pmid9647778>{{cite journal |last=Chen |first=J |coauthors=Peterson R T, Schreiber S L |year=1998 |month=June |title=Alpha 4 associates with protein phosphatases 2A, 4, and 6 |journal=Biochem. Biophys. Res. Commun. |volume=247 |issue=3 |pages=827–32 |location = UNITED STATES| issn = 0006-291X| pmid = 9647778 |doi = 10.1006/bbrc.1998.8792 }}</ref> [[PPP4R1]],<ref name=pmid17353931/><ref name=pmid18715871/><ref name=pmid16085932/> [[CCT5 (gene)|CCT5]],<ref name=pmid18715871/><ref name=pmid16085932/> [[T-complex 1]],<ref name=pmid18715871/><ref name=pmid16085932/> [[REL]],<ref name=pmid9837938>{{cite journal |last=Hu |first=M C |coauthors=Tang-Oxley Q, Qiu W R, Wang Y P, Mihindukulasuriya K A, Afshar R, Tan T H |year=1998 |month=December |title=Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity |journal=J. Biol. Chem. |volume=273 |issue=50 |pages=33561–5 |location = UNITED STATES| issn = 0021-9258| pmid = 9837938 |doi=10.1074/jbc.273.50.33561 }}</ref> [[CCDC6]],<ref name=pmid17353931/><ref name=pmid18715871/> [[TRAF6]]<ref name=pmid18634786>{{cite journal |last=Chen |first=Lu |coauthors=Dong Wei, Zou Tingting, Ouyang Lu, He Guoqing, Liu Yingle, Qi Yipeng |year=2008 |month=August |title=Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6 |journal=FEBS Lett. |volume=582 |issue=19 |pages=2843–9 |location = Netherlands| issn = 0014-5793| pmid = 18634786 |doi = 10.1016/j.febslet.2008.07.014 }}</ref> and [[PPP2R1A]].<ref name=pmid17353931/><ref name=pmid18715871/>
PPP4C has been shown to [[Protein-protein interaction|interact]] with [[CCT2 (gene)|CCT2]],<ref name=pmid18715871>{{cite journal |last=Chen |first=Ginny I |coauthors=Tisayakorn Sally, Jorgensen Claus, D'Ambrosio Lisa M, Goudreault Marilyn, Gingras Anne-Claude |year=2008 |month=October |title=PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4 |journal=J. Biol. Chem. |volume=283 |issue=43 |pages=29273–84 |location = United States| issn = 0021-9258| pmid = 18715871 |doi = 10.1074/jbc.M803443200 |pmc=2662017 }}</ref><ref name=pmid16085932>{{cite journal |last=Gingras |first=Anne-Claude |coauthors=Caballero Michael, Zarske Marcel, Sanchez Amy, Hazbun Tony R, Fields Stanley, Sonenberg Nahum, Hafen Ernst, Raught Brian, Aebersold Ruedi |year=2005 |month=November |title=A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity |journal=Mol. Cell Proteomics |volume=4 |issue=11 |pages=1725–40 |location = United States| issn = 1535-9476| pmid = 16085932 |doi = 10.1074/mcp.M500231-MCP200 }}</ref> [[CCT4]],<ref name=pmid18715871/><ref name=pmid16085932/> [[CCT7]],<ref name=pmid18715871/><ref name=pmid16085932/> [[SMEK2]],<ref name=pmid18715871/><ref name=pmid16085932/><ref name=pmid17353931>{{cite journal |last=Ewing |first=Rob M |coauthors=Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel |year=2007 |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |pages=89 |location = England| issn = | pmid = 17353931 |doi = 10.1038/msb4100134 |pmc=1847948 |issue=1}}</ref> [[CCT6A]],<ref name=pmid18715871/><ref name=pmid16085932/> [[CCT3]],<ref name=pmid18715871/><ref name=pmid16085932/> [[IGBP1]],<ref name=pmid18715871/><ref name=pmid16085932/><ref name=pmid9647778>{{cite journal |last=Chen |first=J |coauthors=Peterson R T, Schreiber S L |year=1998 |month=June |title=Alpha 4 associates with protein phosphatases 2A, 4, and 6 |journal=Biochem. Biophys. Res. Commun. |volume=247 |issue=3 |pages=827–32 |location = United States| issn = 0006-291X| pmid = 9647778 |doi = 10.1006/bbrc.1998.8792 }}</ref> [[PPP4R1]],<ref name=pmid18715871/><ref name=pmid16085932/><ref name=pmid17353931/> [[CCT5 (gene)|CCT5]],<ref name=pmid18715871/><ref name=pmid16085932/> [[T-complex 1]],<ref name=pmid18715871/><ref name=pmid16085932/> [[REL]],<ref name=pmid9837938>{{cite journal |last=Hu |first=M C |coauthors=Tang-Oxley Q, Qiu W R, Wang Y P, Mihindukulasuriya K A, Afshar R, Tan T H |year=1998 |month=December |title=Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity |journal=J. Biol. Chem. |volume=273 |issue=50 |pages=33561–5 |location = United States| issn = 0021-9258| pmid = 9837938 |doi=10.1074/jbc.273.50.33561 }}</ref> [[CCDC6]],<ref name=pmid18715871/><ref name=pmid17353931/> [[TRAF6]]<ref name=pmid18634786>{{cite journal |last=Chen |first=Lu |coauthors=Dong Wei, Zou Tingting, Ouyang Lu, He Guoqing, Liu Yingle, Qi Yipeng |year=2008 |month=August |title=Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6 |journal=FEBS Lett. |volume=582 |issue=19 |pages=2843–9 |location = Netherlands| issn = 0014-5793| pmid = 18634786 |doi = 10.1016/j.febslet.2008.07.014 }}</ref> and [[PPP2R1A]].<ref name=pmid18715871/><ref name=pmid17353931/>


==References==
==References==
{{reflist}}
{{Reflist}}

==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
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*{{cite journal | author=Brewis ND, Cohen PT |title=Protein phosphatase X has been highly conserved during mammalian evolution |journal=Biochim. Biophys. Acta |volume=1171 |issue=2 |pages=231–3 |year=1993 |pmid=1336397 |doi= }}
*{{cite journal | author=Brewis ND, Cohen PT |title=Protein phosphatase X has been highly conserved during mammalian evolution |journal=Biochim. Biophys. Acta |volume=1171 |issue=2 |pages=231–3 |year=1993 |pmid=1336397 |doi= }}
*{{cite journal | author=Brewis ND, Street AJ, Prescott AR, Cohen PT |title=PPX, a novel protein serine/threonine phosphatase localized to centrosomes |journal=EMBO J. |volume=12 |issue=3 |pages=987–96 |year=1993 |pmid=8384557 |doi= | pmc=413299 }}
*{{cite journal | author=Brewis ND, Street AJ, Prescott AR, Cohen PT |title=PPX, a novel protein serine/threonine phosphatase localized to centrosomes |journal=EMBO J. |volume=12 |issue=3 |pages=987–96 |year=1993 |pmid=8384557 |doi= | pmc=413299 }}
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Revision as of 14:38, 14 November 2011

Template:PBB Serine/threonine-protein phosphatase 4 catalytic subunit is an enzyme that in humans is encoded by the PPP4C gene.[1][2]

Template:PBB Summary

Interactions

PPP4C has been shown to interact with CCT2,[3][4] CCT4,[3][4] CCT7,[3][4] SMEK2,[3][4][5] CCT6A,[3][4] CCT3,[3][4] IGBP1,[3][4][6] PPP4R1,[3][4][5] CCT5,[3][4] T-complex 1,[3][4] REL,[7] CCDC6,[3][5] TRAF6[8] and PPP2R1A.[3][5]

References

  1. ^ Bastians H, Krebber H, Hoheisel J, Ohl S, Lichter P, Ponstingl H, Joos S (1997). "Assignment of the human serine/threonine protein phosphatase 4 gene (PPP4C) to chromosome 16p11-p12 by fluorescence in situ hybridization". Genomics. 42 (1): 181–2. doi:10.1006/geno.1997.4693. PMID 9177794. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. ^ "Entrez Gene: PPP4C protein phosphatase 4 (formerly X), catalytic subunit".
  3. ^ a b c d e f g h i j k l Chen, Ginny I (2008). "PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4". J. Biol. Chem. 283 (43). United States: 29273–84. doi:10.1074/jbc.M803443200. ISSN 0021-9258. PMC 2662017. PMID 18715871. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link)
  4. ^ a b c d e f g h i j Gingras, Anne-Claude (2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Mol. Cell Proteomics. 4 (11). United States: 1725–40. doi:10.1074/mcp.M500231-MCP200. ISSN 1535-9476. PMID 16085932. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link)
  5. ^ a b c d Ewing, Rob M (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1). England: 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  6. ^ Chen, J (1998). "Alpha 4 associates with protein phosphatases 2A, 4, and 6". Biochem. Biophys. Res. Commun. 247 (3). United States: 827–32. doi:10.1006/bbrc.1998.8792. ISSN 0006-291X. PMID 9647778. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)
  7. ^ Hu, M C (1998). "Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity". J. Biol. Chem. 273 (50). United States: 33561–5. doi:10.1074/jbc.273.50.33561. ISSN 0021-9258. PMID 9837938. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)CS1 maint: unflagged free DOI (link)
  8. ^ Chen, Lu (2008). "Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6". FEBS Lett. 582 (19). Netherlands: 2843–9. doi:10.1016/j.febslet.2008.07.014. ISSN 0014-5793. PMID 18634786. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)

Further reading

Template:PBB Further reading

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