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== Errors in entry on John P.A. Ioannidis == |
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Dear Candleabracadabra, |
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I realize that some information listed on the Wikipedia article about myself is seriously outdated and there are several wrong/biased additions have been made recently. I certainly do not want to be the final judge of edits and corrections myself. I am trying to find an objective independent appraiser/editor. I see that you had carefully edited the Wikipedia entry on me a while ago, and your edits suggest to me that you were very objective, so I am wondering whether you may wish to consider the following and perhaps make changes as you might see fit. |
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1. The first paragraph says that I am “a professor and chairman at the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine as well as adjunct professor at Tufts University School of Medicine and Professor of Medicine and Director of the Stanford Prevention Research Center at Stanford University School of Medicine.” I had chaired the Department of Hygiene and Epidemiology at the University of Ioannina School of Medicine until 2010 and then I moved to Stanford. Since then I hold the C.F. Rehnborg Chair in Disease Prevention and I am Professor of Medicine, of Health Research and Policy, and of Statistics at Stanford University. While I do have an adjunct appointment at Tufts since 2002, adjunct appointments are certainly not as important as the main appointment at Stanford and they should not take precedence over the primary Stanford appointment. I also have adjunct professor appointments at Harvard School of Public Health and at Imperial College London. So, I think the sentence should become something like, “the C.F. Renhborg Chair in Disease Professor at Stanford University, where he is Professor of Medicine, of Health Research and Policy, and of Statistics, Director of the Stanford Prevention Research Center, and Director of the Meta-Research Innovation Center at Stanford (METRICS). Until 2010 he was Professor and Chairman of the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine and he has held adjunct professor appointments at Tufts (Medicine), Harvard (Epidemiology), and Imperial College London (Epidemiology and Biostatistics).” |
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2. In this same paragraph, the references 1 and 2 are outdated and they should be replaced since they pertain to an old webpage from Ioannina and an old CV at the time I was moving to Stanford. They should be replaced by (1) my Stanford webpage https://med.stanford.edu/profiles/john-ioannidis and (2) the CV that I have uploaded in the same Stanford webpage (curriculum vitae DOC under “Links” on the right side of the webpage). The webpage and the CV offer full documentation and other web and other sources, if any additional need to be quoted. |
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3. The majority of my biography seems to cover in an inaccurate and highly biased manner the discussion of a commentary by Goodman and Greenland and a paper by Jager and Leek: “Statisticians Goodman and Greenland agreed that "many medical research findings are less definitive than readers suspect" but found major flaws in Ioannidis's methods, noting that Ioannidis (who did not collaborate with any statisticians on the article) appeared to have confused alpha level with p value and also built the assumption that most findings are likely to be false into his reasoning, thereby making his logic circular. Therefore Goodman and Greenland rejected Ioannidis' claim as unsupportable by the methods used.[6][7] Ioannidis has responded to this critique.[8] …. In an advance access publication on September 25, 2013 Leah R. Jager of the US Naval Academy's Department of Mathematics and Jeffrey T. Leek of John Hopkins Bloomberg School of Public Health's Department of Biostatistics did a study based on P-values from all 77,430 papers published in 5 major medical journals from 2000 to 2010 and found that "the overall rate of false discoveries among reported results is 14%, contrary to previous claims. We also found that there is not a significant increase in the estimated rate of reported false discovery results over time". The two concluded that "Statistical analysis must allow for false discoveries in order to make claims on the basis of noisy data. But our analysis suggests that the medical literature remains a reliable record of scientific progress" [10].” I think this is an extremely biased and distorted presentation. According to GoogleScholar, there are over 50,000 citations to my work in the scientific literature (http://scholar.google.com/citations?user=A9e6sPYAAAAJ&hl=en&oi=ao). The 2005 PLoS Medicine paper that is discussed is indeed one of my most-cited ones (although not the most-cited), and it has received over 1,800 citations to-date (i.e. <4% of my total citations), while it is also the most-accessed and downloaded article in the history of the Public Library of Science (approaching 1 million hits as you can check in the metrics page in http://www.plosmedicine.org/article/metrics/info%3Adoi%2F10.1371%2Fjournal.pmed.0020124). Among the thousands of enthusiastic and supportive quotes/comments about that specific PLoS Med paper, the ones by Goodman/Greenland and Jager/Leek are highly atypical. To give some objective numbers, the commentary by Goodman/Greenland has received only 25 citations in GoogleScholar and the paper by Jager/Leek has received just 1 (by Goodman). The Jager/Leek paper actually was published in a journal where Leek is the associate editor (I doubt any major journal would have published this otherwise), and it is seriously flawed, as I have shown in detail an extensive published rebuttal in that same journal commenting on the data and methods of Jager/Leek. (Reference: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false. Ioannidis JP. Biostatistics. 2014 Jan;15(1):28-36; discussion 39-45. doi: 10.1093/biostatistics/kxt036. Epub 2013 Sep 25). I think these two sections need to be deleted. |
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4. If for whatever reason one insists of mentioning the Goodman/Greenland commentary, one should probably delete at a minimum “but found major flaws in Ioannidis's methods, noting that Ioannidis (who did not collaborate with any statisticians on the article) appeared to have confused alpha level with p value and also built the assumption that most findings are likely to be false into his reasoning, thereby making his logic circular.” As I clarified above, I am professor of statistics and I teach statistics courses at Stanford and in Ioannina I was director (among others) of the Biostatistics-Biomathematics courses. The sentence above sounds as if I don’t know the 101 of the profession that I practice and I teach and where I am so heavily cited in the scientific literature. Also at a minimum, if for whatever reason one wants to keep some mention to the Jager/Leek paper, one should add after any description of their paper that “Ioannidis has published a rebuttal that demonstrates that Jager/Leek used wrong data and wrong methods, and made wrong inferences.” The reference is: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false. Ioannidis JP. Biostatistics. 2014 Jan;15(1):28-36; discussion 39-45. doi: 10.1093/biostatistics/kxt036. Epub 2013 Sep 25.” |
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5. If one wants to maintain focus on the PLoS Medicine paper, one should probably add something about the “average”, “mainstream” current interpretation of that paper: the estimate that most published research findings are false has been corroborated by several empirical studies on reproducibility of different research fields (e.g. in epidemiology, clinical research, pre-clinical research and beyond), e.g. you may cite the recent Economist issue in October 2013 (Reference: http://www.economist.com/news/briefing/21588057-scientists-think-science-self-correcting-alarming-degree-it-not-trouble), the recent coverage in New York Times (Reference: http://www.nytimes.com/2014/01/21/science/new-truths-that-only-one-can-see.html?_r=0), and the recent series of 5 review articles in the Lancet in January 2014 that reviewed the accumulated evidence that unfortunately 85% of research is wasted (Reference: http://www.thelancet.com/series/research). |
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6. Moreover, if one decides to keep the mention to the Goodman/Greenland and Jager/Leek items, I think it is important to clarify that I am a strong supporter and enthusiast of science and the scientific method, otherwise it sounds as if Goodman/Greenland and Jager/Leek are good crusaders defending science against some monster! E.g. you may add that “Ioannidis has repeatedly stated that scientific investigation is the noblest pursuit (e.g. reference: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0040215), but he stresses that his work aims to identify how to improve the efficiency of the scientific process. (e.g. Reference: http://alumni.stanford.edu/get/page/magazine/article/?article_id=53345)” or something similar. |
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7. The current section External Links lists the old Ioannina webpage (may be deleted) and the adjunct appointment Tufts page. It should at a minimum show the Stanford webpage (https://med.stanford.edu/profiles/john-ioannidis ). If you also want to list Tufts and Harvard and Imperial (there are webpages of mine for all these three) this is OK, but not as essential, my primary appointment is at Stanford. It seems also essential to list the webpage for Stanford Prevention Research Center: http://prevention.stanford.edu/ |
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I thank you in advance for your attention to these suggestions and I would be grateful if you could find some time to make corrections to this Wikipedia entry as you might think fit. |
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Kind regards, |
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John P.A. Ioannidis, MD, DSc |
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C.F. Rehnborg Chair in Disease Prevention |
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Professor of Medicine, of Health Research and Policy, and of Statistics |
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Stanford University |
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[[Special:Contributions/76.126.246.118|76.126.246.118]] ([[User talk:76.126.246.118|talk]]) 00:13, 16 February 2014 (UTC) |
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Revision as of 00:13, 16 February 2014
A request for you to revisit the discussion, as another source has been presented there by another user. (Sent per your comment there stating "the reviews cited are run of the mill...") Since another review was presented after your comment, it is fair for you to see the update in the discussion. Northamerica1000(talk) 19:55, 14 February 2014 (UTC)
- The cookbook author noted in the article is significant. I added a redirect for the title mentioned. The review is a run of the mill one star write up. Candleabracadabra (talk) 23:57, 14 February 2014 (UTC)
My point is that Cover Oregon is the marketplace, not just the website. No doubt the site is a miserable failure, but apparently many people are still able to get coverage via Cover Oregon. I added back your citation and tried to clarify that point a bit more. --Esprqii (talk) 20:36, 14 February 2014 (UTC)
- As you've noted in your edit summary, the website is a critical part of the "marketplace". It's covered in the body of the article and needed to be noted in the opneing paragraph. I believe the enrollment numbers have been low and were delayed as a result? The whole article needs work. And I would appreciate it if you clarified anything that you think I haven't gotten right, but removing sourced content entirely as you did at the John Kitzhaber article isn't appropriate. Candleabracadabra (talk) 23:57, 14 February 2014 (UTC)
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Errors in entry on John P.A. Ioannidis
Dear Candleabracadabra,
I realize that some information listed on the Wikipedia article about myself is seriously outdated and there are several wrong/biased additions have been made recently. I certainly do not want to be the final judge of edits and corrections myself. I am trying to find an objective independent appraiser/editor. I see that you had carefully edited the Wikipedia entry on me a while ago, and your edits suggest to me that you were very objective, so I am wondering whether you may wish to consider the following and perhaps make changes as you might see fit.
1. The first paragraph says that I am “a professor and chairman at the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine as well as adjunct professor at Tufts University School of Medicine and Professor of Medicine and Director of the Stanford Prevention Research Center at Stanford University School of Medicine.” I had chaired the Department of Hygiene and Epidemiology at the University of Ioannina School of Medicine until 2010 and then I moved to Stanford. Since then I hold the C.F. Rehnborg Chair in Disease Prevention and I am Professor of Medicine, of Health Research and Policy, and of Statistics at Stanford University. While I do have an adjunct appointment at Tufts since 2002, adjunct appointments are certainly not as important as the main appointment at Stanford and they should not take precedence over the primary Stanford appointment. I also have adjunct professor appointments at Harvard School of Public Health and at Imperial College London. So, I think the sentence should become something like, “the C.F. Renhborg Chair in Disease Professor at Stanford University, where he is Professor of Medicine, of Health Research and Policy, and of Statistics, Director of the Stanford Prevention Research Center, and Director of the Meta-Research Innovation Center at Stanford (METRICS). Until 2010 he was Professor and Chairman of the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine and he has held adjunct professor appointments at Tufts (Medicine), Harvard (Epidemiology), and Imperial College London (Epidemiology and Biostatistics).” 2. In this same paragraph, the references 1 and 2 are outdated and they should be replaced since they pertain to an old webpage from Ioannina and an old CV at the time I was moving to Stanford. They should be replaced by (1) my Stanford webpage https://med.stanford.edu/profiles/john-ioannidis and (2) the CV that I have uploaded in the same Stanford webpage (curriculum vitae DOC under “Links” on the right side of the webpage). The webpage and the CV offer full documentation and other web and other sources, if any additional need to be quoted. 3. The majority of my biography seems to cover in an inaccurate and highly biased manner the discussion of a commentary by Goodman and Greenland and a paper by Jager and Leek: “Statisticians Goodman and Greenland agreed that "many medical research findings are less definitive than readers suspect" but found major flaws in Ioannidis's methods, noting that Ioannidis (who did not collaborate with any statisticians on the article) appeared to have confused alpha level with p value and also built the assumption that most findings are likely to be false into his reasoning, thereby making his logic circular. Therefore Goodman and Greenland rejected Ioannidis' claim as unsupportable by the methods used.[6][7] Ioannidis has responded to this critique.[8] …. In an advance access publication on September 25, 2013 Leah R. Jager of the US Naval Academy's Department of Mathematics and Jeffrey T. Leek of John Hopkins Bloomberg School of Public Health's Department of Biostatistics did a study based on P-values from all 77,430 papers published in 5 major medical journals from 2000 to 2010 and found that "the overall rate of false discoveries among reported results is 14%, contrary to previous claims. We also found that there is not a significant increase in the estimated rate of reported false discovery results over time". The two concluded that "Statistical analysis must allow for false discoveries in order to make claims on the basis of noisy data. But our analysis suggests that the medical literature remains a reliable record of scientific progress" [10].” I think this is an extremely biased and distorted presentation. According to GoogleScholar, there are over 50,000 citations to my work in the scientific literature (http://scholar.google.com/citations?user=A9e6sPYAAAAJ&hl=en&oi=ao). The 2005 PLoS Medicine paper that is discussed is indeed one of my most-cited ones (although not the most-cited), and it has received over 1,800 citations to-date (i.e. <4% of my total citations), while it is also the most-accessed and downloaded article in the history of the Public Library of Science (approaching 1 million hits as you can check in the metrics page in http://www.plosmedicine.org/article/metrics/info%3Adoi%2F10.1371%2Fjournal.pmed.0020124). Among the thousands of enthusiastic and supportive quotes/comments about that specific PLoS Med paper, the ones by Goodman/Greenland and Jager/Leek are highly atypical. To give some objective numbers, the commentary by Goodman/Greenland has received only 25 citations in GoogleScholar and the paper by Jager/Leek has received just 1 (by Goodman). The Jager/Leek paper actually was published in a journal where Leek is the associate editor (I doubt any major journal would have published this otherwise), and it is seriously flawed, as I have shown in detail an extensive published rebuttal in that same journal commenting on the data and methods of Jager/Leek. (Reference: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false. Ioannidis JP. Biostatistics. 2014 Jan;15(1):28-36; discussion 39-45. doi: 10.1093/biostatistics/kxt036. Epub 2013 Sep 25). I think these two sections need to be deleted. 4. If for whatever reason one insists of mentioning the Goodman/Greenland commentary, one should probably delete at a minimum “but found major flaws in Ioannidis's methods, noting that Ioannidis (who did not collaborate with any statisticians on the article) appeared to have confused alpha level with p value and also built the assumption that most findings are likely to be false into his reasoning, thereby making his logic circular.” As I clarified above, I am professor of statistics and I teach statistics courses at Stanford and in Ioannina I was director (among others) of the Biostatistics-Biomathematics courses. The sentence above sounds as if I don’t know the 101 of the profession that I practice and I teach and where I am so heavily cited in the scientific literature. Also at a minimum, if for whatever reason one wants to keep some mention to the Jager/Leek paper, one should add after any description of their paper that “Ioannidis has published a rebuttal that demonstrates that Jager/Leek used wrong data and wrong methods, and made wrong inferences.” The reference is: Why "An estimate of the science-wise false discovery rate and application to the top medical literature" is false. Ioannidis JP. Biostatistics. 2014 Jan;15(1):28-36; discussion 39-45. doi: 10.1093/biostatistics/kxt036. Epub 2013 Sep 25.” 5. If one wants to maintain focus on the PLoS Medicine paper, one should probably add something about the “average”, “mainstream” current interpretation of that paper: the estimate that most published research findings are false has been corroborated by several empirical studies on reproducibility of different research fields (e.g. in epidemiology, clinical research, pre-clinical research and beyond), e.g. you may cite the recent Economist issue in October 2013 (Reference: http://www.economist.com/news/briefing/21588057-scientists-think-science-self-correcting-alarming-degree-it-not-trouble), the recent coverage in New York Times (Reference: http://www.nytimes.com/2014/01/21/science/new-truths-that-only-one-can-see.html?_r=0), and the recent series of 5 review articles in the Lancet in January 2014 that reviewed the accumulated evidence that unfortunately 85% of research is wasted (Reference: http://www.thelancet.com/series/research). 6. Moreover, if one decides to keep the mention to the Goodman/Greenland and Jager/Leek items, I think it is important to clarify that I am a strong supporter and enthusiast of science and the scientific method, otherwise it sounds as if Goodman/Greenland and Jager/Leek are good crusaders defending science against some monster! E.g. you may add that “Ioannidis has repeatedly stated that scientific investigation is the noblest pursuit (e.g. reference: http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0040215), but he stresses that his work aims to identify how to improve the efficiency of the scientific process. (e.g. Reference: http://alumni.stanford.edu/get/page/magazine/article/?article_id=53345)” or something similar. 7. The current section External Links lists the old Ioannina webpage (may be deleted) and the adjunct appointment Tufts page. It should at a minimum show the Stanford webpage (https://med.stanford.edu/profiles/john-ioannidis ). If you also want to list Tufts and Harvard and Imperial (there are webpages of mine for all these three) this is OK, but not as essential, my primary appointment is at Stanford. It seems also essential to list the webpage for Stanford Prevention Research Center: http://prevention.stanford.edu/
I thank you in advance for your attention to these suggestions and I would be grateful if you could find some time to make corrections to this Wikipedia entry as you might think fit.
Kind regards,
John P.A. Ioannidis, MD, DSc C.F. Rehnborg Chair in Disease Prevention Professor of Medicine, of Health Research and Policy, and of Statistics Stanford University 76.126.246.118 (talk) 00:13, 16 February 2014 (UTC)