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==Amino acids==
==Amino acids==
{{Main|Essential amino acid}}
{{Main|Essential amino acid}}
An essential amino acid is an [[amino acid]] that can not be synthesized ''[[de novo synthesis|de novo]]'' (from scratch) by an organism, and therefore must be supplied in its diet.
An essential amino acid is an [[amino acid]] that cannot be synthesized ''[[de novo synthesis|de novo]]'' (from scratch) by an organism, and therefore must be supplied in its diet. Out of the twenty amino acids, nine cannot be endogenously synthesized by humans: [[phenylalanine]], [[valine]], [[threonine]], [[tryptophan]], [[methionine]], [[leucine]], [[isoleucine]], [[lysine]], and [[histidine]].<ref>{{cite journal |author=Young VR |title=Adult amino acid requirements: the case for a major revision in current recommendations |journal=J. Nutr. |volume=124 |issue=8 Suppl |pages=1517S–1523S |year=1994 |pmid=8064412 |url=http://jn.nutrition.org/cgi/reprint/124/8_Suppl/1517S.pdf}}</ref><ref name="DRI">Dietary Reference Intakes: The Essential Guide to Nutrient Requirements, published by the Institute of Medicine's Food and Nutrition Board, currently available online at http://fnic.nal.usda.gov/dietary-guidance/dietary-reference-intakes/dri-reports</ref>


==Fatty acids==
==Fatty acids==
{{Main|Essential fatty acid}}
{{Main|Essential fatty acid}}
Essential fatty acids (EFAs) are [[fatty acid]]s that humans and other animals must ingest because the body requires them for good health but cannot [[Biosynthesis|synthesize]] them.<ref>{{cite book | title = Modern Nutrition in Health and Disease | edition = 6th | year = 1980 |author1=Robert S. Goodhart |author2=Maurice E. Shils | publisher = Lea and Febinger | location = Philadelphia | isbn = 0-8121-0645-8 | pages = 134–138}}</ref> Only two fatty acids are known to be essential for humans: [[alpha-linolenic acid]] (an [[omega-3 fatty acid]]) and [[linoleic acid]] (an [[omega-6 fatty acid]]).<ref>{{cite book |author1=Whitney Ellie |author2=Rolfes SR | title = Understanding Nutrition | edition = 11th | location = California | publisher = Thomson Wadsworth | year = 2008 | pages = 154}}</ref>
Essential fatty acids (EFAs) are [[fatty acid]]s that humans and other animals must ingest because the body requires them for good health but cannot [[Biosynthesis|synthesize]] them.<ref>{{cite book | title = Modern Nutrition in Health and Disease | edition = 6th | year = 1980 |author1=Robert S. Goodhart |author2=Maurice E. Shils | publisher = Lea and Febinger | location = Philadelphia | isbn = 0-8121-0645-8 | pages = 134–138}}</ref>


==Vitamins==
==Vitamins==
{{Main|Vitamin}}
{{Main|Vitamin}}
Vitamins are organic molecules essential for an organism that are not classified as [[amino acid]]s or [[fatty acids]]. They commonly function as [[enzymatic cofactor]]s, metabolic regulators or [[antioxidants]]. Humans require thirteen vitamins in their diet, most of which are actually groups of related molecules (e.g. [[vitamin E]] includes [[tocopherol]]s and [[tocotrienol]]s).<ref>{{cite journal | author = Brigelius-Flohé R, Traber MG | title = Vitamin E: function and metabolism | journal = FASEB J. | volume = 13 | issue = 10 | pages = 1145–1155 | year = 1999 | pmid = 10385606 | last2 = Traber }}</ref>
Vitamins are organic molecules essential for an organism that are not classified as [[amino acid]]s or [[fatty acids]]. They cMinerals{{Main|Mineral (nutrient)}}

==Minerals==
{{Main|Mineral (nutrient)}}
Minerals are the [[exogenous]] [[chemical element]]s indispensable for an organism which are not provided by the other essential nutrients. The elements provided by essential amino acids, fatty acids and vitamins are [[carbon]], [[hydrogen]], [[oxygen]], [[nitrogen]] and [[sulfur]]. For humans, the "major minerals" are [[calcium]], [[phosphorus]], [[potassium]], [[sodium]], [[chlorine]], and [[magnesium]]. "Minor minerals" include metals such as [[iron]], [[zinc]], [[manganese]] and [[copper]].
Minerals are the [[exogenous]] [[chemical element]]s indispensable for an organism which are not provided by the other essential nutrients. The elements provided by essential amino acids, fatty acids and vitamins are [[carbon]], [[hydrogen]], [[oxygen]], [[nitrogen]] and [[sulfur]]. For humans, the "major minerals" are [[calcium]], [[phosphorus]], [[potassium]], [[sodium]], [[chlorine]], and [[magnesium]]. "Minor minerals" include metals such as [[iron]], [[zinc]], [[manganese]] and [[copper]].



Revision as of 18:40, 27 March 2017

An essential nutrient is a nutrient required for normal physiological function that cannot be synthesized by the body, and thus must be obtained from a dietary source.[1] Apart from water, which is universally required for the maintenance of homeostasis,[2] essential nutrients are indispensable for the metabolic processes of cells, as well as the proper physiological functions of tissues and organs.[3] In the case of humans, there are nine amino acids, two fatty acids, thirteen vitamins and fifteen minerals that are considered essential nutrients.[3] In addition, there are several molecules that are considered conditionally essential nutrients since they are indispensable in certain developmental and pathological states.[3][4][5]

Amino acids

An essential amino acid is an amino acid that can not be synthesized de novo (from scratch) by an organism, and therefore must be supplied in its diet.

Fatty acids

Essential fatty acids (EFAs) are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them.[6]

Vitamins

Vitamins are organic molecules essential for an organism that are not classified as amino acids or fatty acids. They cMinerals

Minerals are the exogenous chemical elements indispensable for an organism which are not provided by the other essential nutrients. The elements provided by essential amino acids, fatty acids and vitamins are carbon, hydrogen, oxygen, nitrogen and sulfur. For humans, the "major minerals" are calcium, phosphorus, potassium, sodium, chlorine, and magnesium. "Minor minerals" include metals such as iron, zinc, manganese and copper.

Conditionally essential nutrients

Conditionally essential nutrients are certain organic molecules that can normally be synthesized by an organism, but under certain conditions such biosynthesis is not enough to prevent a deficiency syndrome. In humans, such conditions include prematurity, limited nutrient intake, rapid growth, and certain disease states.[4] Choline, inositol, taurine, arginine, glutamine and nucleotides are classified as conditionally essential and are particularly important in neonatal diet and metabolism.[4]

References

  1. ^ "What is an essential nutrient?". NetBiochem Nutrition, University of Utah.
  2. ^ Jéquier, E; Constant, F (2 September 2009). "Water as an essential nutrient: the physiological basis of hydration". European Journal of Clinical Nutrition. 64 (2): 115–123. doi:10.1038/ejcn.2009.111.
  3. ^ a b c Chipponi, JX; Bleier, JC; Santi, MT; Rudman, D (May 1982). "Deficiencies of essential and conditionally essential nutrients". American Journal of Clinical Nutrition. 35 (5 Suppl): 1112–1116. PMID 6805293.
  4. ^ a b c Carver, Jane (2006). "Conditionally essential nutrients: choline, inositol, taurine, arginine, glutamine and nucleotides". Neonatal Nutrition and Metabolism. Cambridge, UK: Cambridge University Press. pp. 299–311.
  5. ^ Kendler, BS (2006). "Supplemental conditionally essential nutrients in cardiovascular disease therapy". Journal of Cardiovascular Nursing. 21 (1): 9–16. PMID 16407731.
  6. ^ Robert S. Goodhart; Maurice E. Shils (1980). Modern Nutrition in Health and Disease (6th ed.). Philadelphia: Lea and Febinger. pp. 134–138. ISBN 0-8121-0645-8.