Haemodialysis-associated amyloidosis: Difference between revisions
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==Prevention== |
==Prevention== |
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Low copper dialysis is theorized to prevent or delay onset.<ref name="urlBU | Amyloid Treatment & Research Program | Doctors | Clinical Features | Aß2M Amyloidosis">{{cite web |url=http://www.bu.edu/amyloid/doctors/features/clinical-ab2.html |title=BU Amyloid Treatment & Research Program |work= |accessdate=}}</ref> |
Low copper dialysis is theorized to prevent or delay onset.<ref name="urlBU | Amyloid Treatment & Research Program | Doctors | Clinical Features | Aß2M Amyloidosis">{{cite web |url=http://www.bu.edu/amyloid/doctors/features/clinical-ab2.html |title=BU Amyloid Treatment & Research Program |work= |accessdate= |deadurl=yes |archiveurl=https://web.archive.org/web/20080720044306/http://www.bu.edu/amyloid/doctors/features/clinical-ab2.html |archivedate=2008-07-20 |df= }}</ref> |
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== See also == |
== See also == |
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Revision as of 20:52, 27 October 2017
| Haemodialysis-associated amyloidosis | |
|---|---|
| Specialty | Immunology  |
Haemodialysis-associated amyloidosis is a form of systemic amyloidosis associated with chronic kidney failure.[1]
Presentation
Long-term haemodialysis results in a gradual accumulation of β2 microglobulin, a serum protein, in the blood.[2] It accumulates because it is unable to cross the dialysis filter.
Affected individuals usually present after 5 years of dialysis rarely before that. The tendency of haemodialysis-associated amyloidosis is to be articular in general affecting the joints.
Prevention
Low copper dialysis is theorized to prevent or delay onset.[3]
See also
References
- ^ Miyata T, Oda O, Inagi R, et al. (September 1993). "beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis". J. Clin. Invest. 92 (3): 1243–52. doi:10.1172/JCI116696. PMC 288264. PMID 8376584.
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ "BU Amyloid Treatment & Research Program". Archived from the original on 2008-07-20.
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