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Isobutylamine: Difference between revisions

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Added mention of the structural and metabolic relationship between isobutylamine and valine.
Added note about the antipsychotic effects of isobutylamine, with a source.
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'''Isobutylamine''' is an organic chemical compound (specifically, an [[amine]]) with the formula (CH<sub>3</sub>)<sub>2</sub>CHCH<sub>2</sub>NH<sub>2</sub>, and occurs as a colorless liquid.<ref>[http://www.chemicalbook.com/ChemicalProductProperty_EN_CB9211238.htm Isobutylamine] chemicalbook.com</ref><ref>[http://www.chemblink.com/products/78-81-9.htm Isobutylamine] Chemblink.com</ref> Isobutylamine is one of the four isomeric amines of [[butane]], the others being [[N-Butylamine|''n''-butylamine]], [[sec-butylamine|''sec''-butylamine]] and [[Tert-Butylamine|''tert''-butylamine]]. It is the decarboxylated form of the [[amino acid]] [[valine]], and the product of the metabolism thereof by the enzyme [[valine decarboxylase]].
'''Isobutylamine''' is an organic chemical compound (specifically, an [[amine]]) with the formula (CH<sub>3</sub>)<sub>2</sub>CHCH<sub>2</sub>NH<sub>2</sub>, and occurs as a colorless liquid.<ref>[http://www.chemicalbook.com/ChemicalProductProperty_EN_CB9211238.htm Isobutylamine] chemicalbook.com</ref><ref>[http://www.chemblink.com/products/78-81-9.htm Isobutylamine] Chemblink.com</ref> Isobutylamine is one of the four isomeric amines of [[butane]], the others being [[N-Butylamine|''n''-butylamine]], [[sec-butylamine|''sec''-butylamine]] and [[Tert-Butylamine|''tert''-butylamine]]. It is the decarboxylated form of the [[amino acid]] [[valine]], and the product of the metabolism thereof by the enzyme [[valine decarboxylase]]. Isobutylamine also has [[antipsychotic]] effects.<ref>{{Cite web|url=https://www.cdc.gov/niosh-rtecs/NP970FE0.html|title=RTECS:NP9900000 - Isobutylamine - The Registry of Toxic Effects of Chemical Substances {{!}} CDC/NIOSH|website=www.cdc.gov|language=en-us|access-date=2017-11-14}}</ref>


==References==
==References==

Revision as of 05:36, 14 November 2017

Isobutylamine
Skeletal formula of isobutylamine
Names
Preferred IUPAC name
2-Methylpropan-1-amine
Other names
(2-Methylpropyl)amine
Identifiers
3D model (JSmol)
3DMet
385626
ChEBI
ChemSpider
ECHA InfoCard 100.001.042 Edit this at Wikidata
EC Number
  • 201-145-4
81862
KEGG
MeSH isobutylamine
RTECS number
  • NP9900000
UNII
UN number 1214
  • InChI=1S/C4H11N/c1-4(2)3-5/h4H,3,5H2,1-2H3 checkY
    Key: KDSNLYIMUZNERS-UHFFFAOYSA-N checkY
  • CC(C)CN
Properties
C4H11N
Molar mass 73.139 g·mol−1
Appearance Colorless liquid
Odor Fishy, ammoniacal
Density 736 mg mL−1
Melting point −86.6 °C; −124.0 °F; 186.5 K
Boiling point 67 to 69 °C; 152 to 156 °F; 340 to 342 K
Miscible
-59.8·10−6 cm3/mol
1.397
Viscosity 500 μPa s (at 20 °C)
Thermochemistry
194 J K−1 mol−1
−133.0–−132.0 kJ mol−1
−3.0139–−3.0131 MJ mol−1
Hazards
GHS labelling:
GHS02: Flammable GHS05: Corrosive GHS06: Toxic
Danger
H225, H301, H314
P210, P280, P301+P310, P305+P351+P338, P310
Flash point −9 °C (16 °F; 264 K)
Lethal dose or concentration (LD, LC):
224 mg kg−1 (oral, rat)
Related compounds
Related alkanamines
Related compounds
2-Methyl-2-nitrosopropane
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Isobutylamine is an organic chemical compound (specifically, an amine) with the formula (CH3)2CHCH2NH2, and occurs as a colorless liquid.[1][2] Isobutylamine is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and tert-butylamine. It is the decarboxylated form of the amino acid valine, and the product of the metabolism thereof by the enzyme valine decarboxylase. Isobutylamine also has antipsychotic effects.[3]

References

  1. ^ Isobutylamine chemicalbook.com
  2. ^ Isobutylamine Chemblink.com
  3. ^ "RTECS:NP9900000 - Isobutylamine - The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH". www.cdc.gov. Retrieved 2017-11-14.