KIAA0157

ABRAXAS2
Identifiers
Aliases	ABRAXAS2, ABRO1, KIAA0157, FAM175B, family with sequence similarity 175 member B, abraxas 2, BRISC complex subunit
External IDs	OMIM: 611144; MGI: 1926116; HomoloGene: 12970; GeneCards: ABRAXAS2; OMA:ABRAXAS2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	124,836,667 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	132,486,840 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; middle temporal gyrus; ; Skeletal muscle tissue of biceps brachii; ; Brodmann area 23; ; gonad; ; deltoid muscle; ; gastrocnemius muscle; ; Achilles tendon; ; parietal pleura; ; visceral pleura;
	Top expressed in
	Paneth cell; ; superior cervical ganglion; ; otolith organ; ; utricle; ; hand; ; ureter; ; foot; ; temporal muscle; ; facial motor nucleus; ; genital tubercle;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding; polyubiquitin modification-dependent protein binding; protein binding;
Cellular component	cytoplasm; centrosome; spindle pole; BRISC complex; spindle pole centrosome; midbody; microtubule; cytoskeleton; nucleus; microtubule minus-end; cytosol;
Biological process	chromosome segregation; cell division; mitotic spindle assembly; response to ischemia; protein K63-linked deubiquitination; cell cycle; attachment of spindle microtubules to kinetochore; protein deubiquitination; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	23172
	109359
	ENSG00000165660
	ENSMUSG00000030965
	Q15018
	Q3TCJ1
	NM_032182
	NM_198017
	NP_115558
	NP_932134
	Wikidata
View/Edit Human	View/Edit Mouse

BRISC complex subunit Abro1 is a protein that in humans is encoded by the FAM175B gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165660 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030965 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Seki N, Tanaka A, Ishikawa K, Nomura N (Mar 1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. doi:10.1093/dnares/2.4.167. PMID 8590280.
^ "Entrez Gene: KIAA0157 KIAA0157".

Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000165660 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030965 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8590280-5] Nagase T, Seki N, Tanaka A, Ishikawa K, Nomura N (Mar 1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. doi:10.1093/dnares/2.4.167. PMID 8590280.

[entrez-6] "Entrez Gene: KIAA0157 KIAA0157".

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References

Further reading