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This is an old revision of this page, as edited by 250GP (talk | contribs) at 13:22, 24 April 2010. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

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Cleanup

Added cleanup tag to Evolution of Androgenic Alopecia, as it reads more like a lecture than an encyclopedia entry. I don't know enough about the subject matter to make changes but something should be done. —Preceding unsigned comment added by 131.107.0.101 (talk) 22:58, 18 November 2008 (UTC)[reply]

genetic

Male pattern baldness is a genetic disorder? Someone should probably explain that. . . . 68.6.85.167 08:54, 20 June 2006 (UTC)[reply]

Well it is, in a sense. Sure, it's not a serious genetic disorder like Cystic Fibrosis or Sickle-cell anaemia. But it is inherited and it could be considered a disorder in so much that it causes effects that aren't really meant to happen. --Burbster 17:49, 14 July 2006 (UTC)[reply]


There are social theorists who argue that it was 'meant to happen.' Thus, the reason for the pattern in men while women's hair loss is diffuse. Perhaps 'genetic trait' would be better term. Perhaps there's an advantage to removing older men from mate competition, preserving them and allowing them to be parents rather than possibly getting killed? Baldness is correlated with other serious disorders, though.

Small Correction: "are X linked and thus inherited from one's mother's father" should simply read "... from one's mother". Men inherit X linked traits from their mothers, but since women get an X chromosome from both parents a gene on a man's X chromosome could be inherited from either of the man's maternal grandparents. Reference: Genes VII by Benjamin Lewin.

removed

Removed People with this Condition... the two that were listed do not have androgenetic alopecia, they have alopecia universalis. There IS a difference. MMoyer 18:22, 15 November 2006 (UTC)[reply]

X and Y

I think the comments about a male person's X chromosome being inherited from his mother and the Y chromosome being inherited from his father, are over-simplified to the point of being misleading. A male will inherit 22 X chromosomes from his father and 1 Y chromosome. Have the genes responsible for Androgenetic alopecia been shown to be in the gonosome (23rd pair)? Sledge68 19:40, 18 May 2007 (UTC)[reply]

Um, Sledge68, that is simply incorrect... a male will inherit 22 autosomal chromosomes from his father and a Y chromsome; the other 22 autosomal chromosomes and the X will come from his mother. Blackmetalbaz 12:30, 21 September 2007 (UTC)[reply]

Castration as a possible treatment

Should castration be listed as a treatment? Maybe I'm being squeamish but I don't think it's a treatment that anyone would undergo(at least not for baldness). Are there any known instances of indiviuals undergoing castration to specifically halt the onset of baldness? Otherwise I think that should be removed. Donquigleone (talk) 23:18, 14 January 2008 (UTC)[reply]

No, baldness has nothing to do with testosterone--250GP (talk) 13:39, 12 April 2010 (UTC)[reply]

Effectiveness of Saw Palmetto vs Finesteride

Why is Saw Palmetto considered less effective than finesteride? Saw Palmetto inhibits both isoforms of 5alpha-reductase. Finesteride inhibits only one. --Ryan Wise (talk) 05:40, 16 March 2008 (UTC)[reply]


Please help!

هل يمكن أن يحدث الصلع الذكوري أو الوراثي بدون تراجع خط الشعر الأمامي؟ هل هناك فرق بين الصلع الوراثي والذكوري؟ هل يمكن أن يحدث الصلع الأنثوي إلى رجل؟ —Preceding unsigned comment added by 41.234.227.231 (talk) 04:39, 15 April 2008 (UTC)[reply]

Horrible wording

I don't like how one part of this section is worded "Androgenic alopecia (also known as androgenetic alopecia or alopecia androgenetica) is a common form of hair loss in both male and female humans" Male and female humans? As opposed to all the other humans?76.226.115.48 (talk) 10:09, 25 August 2008 (UTC)[reply]

This article is absolutely false

There are many mistakes in this article, here is some of the most ridicolus mistakes:

1) Androgens (especially testosterone with the UNIQUE exception of DHT) have nothing to do with baldness. It was an old theory, now it is clear that men or women with baldness have LOW TESTOSTERONE LEVELS (I will insert the articles), and this is clear watching the typical body of bald men with the typical muscle mass deficiency, instead the FIRST free testosterone effect is building of muscle mass

2) It is written that bald men have more testosterone, FALSE! It is true the contrary, bald men have low testosterone levels (hypogonadism) and exactly for this reason have often diabetes mellitus

3) It is written that IGF-I (according to an old citation, in pefect contrast to new scientific articles) has a bad effect on hairs, absolutely false, bald men or women have low IGF/I levels, and the decrease of IGF-I levels lead to baldness, alwais! IGF-I IS THE MOST IMPORTANT HORMONE FOR HAIRS!

4) If the testosterone and IGF-I levels were linked to baldness, aged people should be protected from baldness (because aged people have andropause and somatopause), it is true the contrary of course

5) According to this article it seems that women are partially procted from baldness due to estrogens, that's FALSE! Aged women have less estrogens than old men. Women have usually more IGF-I than men, this is the true reason

I also recommed to use new citations. I will insert later new citations.--250GP (talk) 13:36, 12 April 2010 (UTC)[reply]

I've remod ridicolous claims about links testosterone-baldness, I've inserted some true sentence and later I will insert other citations--250GP (talk) 16:57, 12 April 2010 (UTC)[reply]

You've made some very bold changes to the article based on a single reference. I don't have access to the article you've cited, but from the text in the abstract, it does not appear that the article supports your claims. The purpose of the cited study was not to find a cause of androgenic alopecia, but to establish whether there is a correlation between AGA and other health risks. The established cause of AGA is a sensitivity of hair follicles to DHT -- the fact that the control group in the study had higher testosterone levels does not disprove this established hypothesis. I'm going to revert your changes for now. Please discuss them here at greater length before reintroducing them. WikiDan61ChatMe!ReadMe!! 17:18, 12 April 2010 (UTC)[reply]

Instead it disprove, in 2010, not in 1900...it is clear that bald people have less testosterone than normal, I will revert the edit, and tomorrow I will insert other publications (no problem to find other citations if you want)...it is absurd that in 2010 there are people who really think that bald people have more testosterone and are more viril...--250GP (talk) 18:10, 12 April 2010 (UTC)[reply]

The belief that bald people have more testosterone may well be false -- their follicles are simply more sensitive to the testosterone that they have. However, the study you cite does not claim that bald people have less testosterone. It claims that in the limited sample of 160 men in that one study, that the free testosterone level was higher in the control group than in the case group. This is not a sufficient sample to make broad claims. You keep claiming you will add more citations tomorrow. There is no need to rush to add unverified claims. When you have the citations you need to verify your point, Wikipedia will still be here and you can add your information then. Until you have proper verification, please do not add poorly sourced claims and misinterpretations. WikiDan61ChatMe!ReadMe!! 19:13, 12 April 2010 (UTC)[reply]

Ok, later I will insert the citations...but the belief that bald men are more sensitive to testosterone is absurd (it means that with low testosterone levels they have a lot of muscle mass. this is obviously false). Testosterone has no negative effects on hairs (that's perfectly established), testosterone, unlike DHT, is primarly an anabolic hormone, it means it increases proteic synthesism, therefore hair tissue. DHT is the inactive form of testosterone (at least from an anabolic point of view). If the nonbald men have more free testosterone than bald men it proves that bald men have less testosterone (for this reason thay are bald and they easily have erectile disfunction, diabetes mellitus and osteoporosis).

I also would like to insert informations about the hormones that can really cause baldness (cortisol and somatostatine) --250GP (talk) 22:14, 12 April 2010 (UTC)[reply]

Bald men have LOWER testosterone levels

According to the most recent pubblications, bald men have lower testosterone levels (hypogonadism) and this can lead to the typical hypogonadism-related diseases (diabetes mellitus, osteoporosis, cardiocirculatory diseases, dementia and so on), therefore I've inserted two citations that confirm this.

I also would suggest to concentrate arguments to hormones that strongly affect hair life (such as somatotropin and cortisol)--250GP (talk) 13:22, 24 April 2010 (UTC)[reply]