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Pauline Johnson (immunologist)

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This is an old revision of this page, as edited by SmokeyJoe (talk | contribs) at 23:48, 16 April 2020 (Submitting (AFCH 0.9.1)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

  • Comment: I've posted this draft at WIR to see if someone can clean it up and move it to article space.ThatMontrealIP (talk) 23:23, 16 April 2020 (UTC)
  • Comment: Linked in is NOT a reliable source! Theroadislong (talk) 22:24, 16 April 2020 (UTC)
  • Comment: There is only one independent source, more are needed I think. Theroadislong (talk) 21:03, 16 April 2020 (UTC)
  • Comment: I am declining this draft because it has not been reworked as requested by User:DGG, as is evidenced by the subject still being referred to as Dr. Johnson. We know that she has a Ph.D., but we do not put Dr. in front of the names of physicians or scientists; we state what their education is.
    Johnson almost certainly satisfies academic notability. It appears that a draft by this paid editor is never going to satisfy the second pillar of Wikipedia. I am not rejecting this draft, because a neutral editor should be able to clean it up. I am not requesting that this draft be deleted, because a neutral editor should be able to clean it up. I am not that neutral editor, because I am involved and annoyed.
    I have requested a topic-ban against this paid editor continuing to submit this draft, which is wasting the time of the reviewers. Robert McClenon (talk) 16:37, 16 April 2020 (UTC)
  • Comment: Johnson is probably notable , but this is a a promotional press release, not an encyclopedia article. Remove the information about her hobbies. don't keep calling her "Dr." postdoc awards are trivial . Don't ise full capitals for authors names. AND the way to show notability is to indicate the citations for his 4 or 5 most cited articles, using data from google Scholar or Scopus or ISI.
    If you're going being paid for writing articles, learn how to do it right. DGG ( talk ) 07:23, 15 April 2020 (UTC)
This article is about the Canadian microbiologist. For the Canadian poet and actress, see E. Pauline Johnson.
Pauline Johnson
Born
United Kingdom
Alma materLiverpool University
University of Dundee
Oxford University
Salk Institute
Known forWork on lymphocyte cell surface molecules and hyaluronan
Scientific career
FieldsImmunology
InstitutionsUniversity of British Columbia

Pauline Johnson (born in Yorkshire, England) is an immunologist and microbiologist at the University of British Columbia.[1] Her research focuses on innate and adaptive immune mechanisms — in particular, the mobility of proteins in membranes, lymphocyte cell surface molecules, T cell signalling, leukocyte adhesion, and macrophages in lung inflammation.[1]

Education

Johnson earned a BSc in biochemistry from Liverpool University in 1980, and a Ph.D from the University of Dundee in 1983.[1][2] Her Ph.D. project was to determine the lateral and rotational mobility of membrane components measured by fluorescence recovery after photobleaching and fluorescence depletion recovery. [3]

She was a post-doctoral fellow at the Salk Institute in California, US under the supervision of Professor Ian Trowbridge and at the MRC Cellular Immunology Unit at the University of Oxford, U.K. under the supervision of Professor Alan F. Williams[4] before joining the faculty at the University of British Columbia in 1991.[2]

Career and research

Johnson helped to establish the function of CD45 as a critical protein tyrosine phosphatase in T cell activation [5] and defined the mechanisms regulating the interactions of the cell adhesion molecule CD44 with the matrix component, hyaluronan.[6]

Her research in 2020 uses mouse models of lung disease to study the function of macrophages and the cell matrix in infection, inflammation, and cancer.[1]

She held an MRC Scientist Award and was Co-Director of the Infection, Inflammation and Immunity Research Group at the Life Science Institute at UBC (2003-2009).[2] She has served multiple times on the CIHR Immunology and Transplantation panel, including as Scientific Officer, as well as on other national and international review panels. She is a member of the CIHR III Institute Advisory Board (III institute = Inflammation, infection and immunity CIHR Institute).[2]

Fellowships and awards

  • Cancer Research Institute Fellowship, American Cancer Research Institute, 1987
  • MRC Scientist Award, MRC of Canada, 1999-2004
  • Women in Science Award for Community Leadership and Scientific Excellence, Minerva Foundation for B.C. Women, 2013[7]

Publications

  • Johnson, P. & Garland, P. B. (1981). "Depolarisation of fluorescence depletion. A microscopic method for measuring rotational diffusion of membrane proteins on the surface of a single cell". FEBS Lett. 132 (2): 252–256. doi:10.1016/0014-5793(81)81172-6. PMID 6170530.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Johnson, P., Ostergaard, H. L., Wasden, C. & Trowbridge, I. S. (1992). "Mutational analysis of CD45, a leukocyte specific tyrosine phosphatase". Journal of Biological Chemistry. 267 (12): 8035–8041. PMID 1314815.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Samarakoon, A., SHIM, Y. A., Dosanjh, M, Crickmer, M., Labontè-Raymond, C., Arif, A.A. & Johnson, P. (2016). "CD45 regulates GM-CSF, retinoic acid and T cell homing in intestinal inflammation". Mucosal Immunology. 9 (6): 1514–1527. doi:10.1038/mi.2016.23. PMID 27007678.{{cite journal}}: CS1 maint: multiple names: authors list (link)

Refrences

  1. ^ a b c d http://lsi.ubc.ca/person/pauline-johnson/
  2. ^ a b c d https://cihr-irsc.gc.ca/e/50755.html#pauline_johnson
  3. ^ Johnson, P. & Garland, P. B. (1981). "Depolarisation of fluorescence depletion. A microscopic method for measuring rotational diffusion of membrane proteins on the surface of a single cell". FEBS Lett. 132 (2): 252–256. doi:10.1016/0014-5793(81)81172-6. PMID 6170530.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ https://www.semanticscholar.org/paper/Alan-Frederick-Williams.-25-May-1945-–-9-April-1992-Crumpton/b4574e3cec2e7e6d5fb1b2b602446868e64b4e44
  5. ^ Johnson, P., Ostergaard, H. L., Wasden, C. & Trowbridge, I. S. (1992). "Mutational analysis of CD45, a leukocyte specific tyrosine phosphatase". Journal of Biological Chemistry. 267 (12): 8035–8041. PMID 1314815.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ Maiti, A., Maki, G. & Johnson P. (1998). "TNF-α induction of CD44-mediated leukocyte adhesion by sulfation". Science. 282 (5390): 941–943. doi:10.1126/science.282.5390.941. PMID 9794764.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. ^ "Announcing the Honourees for Women In™ Science". Minerva BC.


Category:Living people Category:Immunologists Category:University of British Columbia faculty

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