Talk:Diclofenac

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Removal of 3D animation

3D structures are derived, and should not appear without details of the source of the 3D structure coordinates, or, minimally, of the computations performed to generate the 3D structures from the 2D map of atoms and connectivities (line angle structure, as shown in infobox). Otherwise such 3D structures are unsourced WP:OR. This spinning 3D structure — with its inexplicably determined dihedral and bond angles — is such a case of unpublished, and undocumented original research. As well, it presents the carboxylic acid (protio) form of the compound, when the title compound is almost inevitably a salt form. Le Prof 71.239.87.100 (talk) 01:44, 8 September 2014 (UTC)[reply]

COX-2 selective or not?

Under mechanism of action:

... use of some COX-2 inhibitors with their adverse effects has led to massive numbers of patient family lawsuits alleging wrongful death by heart attack, yet other significantly COX-selective NSAIDs, such as diclofenac ...

It says that diclofenac in COX-selective. Does that mean COX-2 selective? That would seem to conflict this under cardiac side effects:

... Use of the nonselective NSAID diclofenac ...

146.255.183.82 (talk) 13:34, 4 February 2016 (UTC)[reply]

External links modified

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Cosmos magazine: associated with 50% hike in heart risk compared to non-users.

Popular painkiller linked to cardiac risk Axylus.arisbe (talk) 10:15, 10 September 2018 (UTC)[reply]

missing verb

introduced as Voltaren by Ciba-Geigy (now Novartis) in 1973, now ?!? by Glaxo SmithKline.[51]

--Maxus96 (talk) 18:31, 11 July 2019 (UTC)[reply]

diclofenac

Diclofenac was patented in 1965 by Ciba-Geigy

Don't see how this is possible as CIBA-Geigy did not exist in 1965. CIBA (acronym for Chemical Industries Basle should be in capital letters) CIBA and Geigy merged in 1970. I was there.

2601:18E:C401:D060:1DF4:35FD:FA93:5E7E (talk) 17:38, 27 May 2020 (UTC)[reply]

Onset time gel

I used this citation: https://www.youdrugstore.com/health/voltaren-gel-usage.html

If this citation isn't good enough, please let me know why and ping me so i see your reply.--Hiveir (talk) 19:43, 1 June 2020 (UTC)[reply]