2'-Deamino-2'-hydroxyneamine transaminase
| 2'-Deamino-2'-hydroxyneamine transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.94 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2'-Deamino-2'-hydroxyneamine transaminase (EC 2.6.1.94, kacL (gene)) is an enzyme with systematic name 2'-deamino-2'-hydroxyneamine:2-oxoglutarate aminotransferase.[1] This enzyme catalyses the following chemical reaction
- 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate
The reaction occurs in vivo in the opposite direction.
References
- ^ Park, J.W.; Park, S.R.; Nepal, K.K.; Han, A.R.; Ban, Y.H.; Yoo, Y.J.; Kim, E.J.; Kim, E.M.; Kim, D.; Sohng, J.K.; Yoon, Y.J. (2011). "Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation". Nat. Chem. Biol. 7: 843–852. doi:10.1038/nchembio.671. PMID 21983602.
External links
- 2'-deamino-2'-hydroxyneamine+transaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)