The 2006 Estoril Open was a tennis tournament played on outdoor clay courts. This event was the 17th edition of the Estoril Open, included in the 2006 ATP Tour International Series and in the 2006 WTA Tour Tier IV Series. Both the men's and the women's events took place at the Estoril Court Central, in Oeiras, Portugal, from May 1 through May 8, 2006.
David Nalbandian defeated Nikolay Davydenko, 6–3, 6–4
Zheng Jie defeated Li Na, 6–7(5–7), 7–5, retired
Lukáš Dlouhý / Pavel Vízner defeated Lucas Arnold / Leoš Friedl, 6–3, 6–1
Li Ting / Sun Tiantian defeated Gisela Dulko / María Sánchez Lorenzo, 6–2, 6–2