Pedro de Medina's Arte de navegar is published in Valladolid, the first treatise on the art of navigation to be published in Europe.
Physiology and medicine
Charles Estienne publishes De dissectione partium corporis humani, libri tres, including a description of the venous valves of the liver.
Ambroise Paré publishes his first book, a treatise on battlefield medicine, La méthode de traicter les playes faictes par hacquebutes et aultres bastons à feu et de celles qui sont faictes par flèches, dardz et semblables, in Paris.