CAP2

CAP2
Identifiers
Aliases	CAP2, CAP, adenylate cyclase-associated protein, 2 (yeast), cyclase associated actin cytoskeleton regulatory protein 2
External IDs	OMIM: 618385; MGI: 1914502; HomoloGene: 101397; GeneCards: CAP2; OMA:CAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	17,557,780 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	46,803,757 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; Brodmann area 23; ; Skeletal muscle tissue of rectus abdominis; ; vastus lateralis muscle; ; endothelial cell; ; glutes; ; deltoid muscle; ; muscle of thigh; ; gastrocnemius muscle; ; frontal pole;
	Top expressed in
	muscle of thigh; ; triceps brachii muscle; ; vastus lateralis muscle; ; temporal muscle; ; olfactory tubercle; ; primary motor cortex; ; dentate gyrus; ; Region I of hippocampus proper; ; gastrocnemius muscle; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; actin binding; adenylate cyclase binding; identical protein binding;
Cellular component	plasma membrane; membrane; cortical actin cytoskeleton; postsynaptic density;
Biological process	establishment or maintenance of cell polarity; cytoskeleton organization; signal transduction; activation of adenylate cyclase activity; actin polymerization or depolymerization; cell morphogenesis; regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Orthologs
	10486
	67252
	ENSG00000112186
	ENSMUSG00000021373
	P40123
	Q9CYT6
	NM_006366; NM_001363533; NM_001363534
	NM_026056
	NP_006357; NP_001350462; NP_001350463
	NP_080332
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene.^[5]^[6]^[7]

Function

This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin.^[7]

Interactions

CAP2 has been shown to interact with CAP1.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112186 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021373 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yu G, Swiston J, Young D (Jun 1994). "Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins". Journal of Cell Science. 107 (6): 1671–8. doi:10.1242/jcs.107.6.1671. PMID 7962207.
^ ^a ^b Hubberstey A, Yu G, Loewith R, Lakusta C, Young D (Jun 1996). "Mammalian CAP interacts with CAP, CAP2, and actin". Journal of Cellular Biochemistry. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950. S2CID 46076387.
^ ^a ^b "Entrez Gene: CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)".

External links

Human CAP2 genome location and CAP2 gene details page in the UCSC Genome Browser.

Function

Interactions

References

External links

Further reading