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TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

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TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)
Identifiers
EC no.5.3.2.3
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TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming) (EC 5.3.2.3, dTDP-6-deoxy-hex-4-ulose isomerase, TDP-6-deoxy-hex-4-ulose isomerase, FdtA) is an enzyme with systematic name dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose isomerase.[1][2] This enzyme catalyses the following chemical reaction

dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose

The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose.

References

  1. ^ Pfoestl A, Hofinger A, Kosma P, Messner P (July 2003). "Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T". The Journal of Biological Chemistry. 278 (29): 26410–7. doi:10.1074/jbc.m300858200. PMID 12740380.
  2. ^ Davis ML, Thoden JB, Holden HM (June 2007). "The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase". The Journal of Biological Chemistry. 282 (26): 19227–36. doi:10.1074/jbc.m702529200. PMID 17459872.

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