Guvacine
Appearance
![]() | |
Names | |
---|---|
IUPAC name
1,2,3,6-Tetrahydropyridine-5-carboxylic acid
| |
Identifiers | |
3D model (JSmol)
|
|
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C6H9NO2 | |
Molar mass | 127.143 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Guvacine is an alkaloid in areca nuts.[1]It is the N-demethylated derivative of arecaidine, which is found in areca nuts as well.It is GABA uptake inhibitor.[2]
References
- ^ Voigt, V; Laug, L; Zebisch, K; Thondorf, I; Markwardt, F; Brandsch, M (2013). "Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1)". The Journal of Pharmacy and Pharmacology. 65 (4): 582–90. doi:10.1111/jphp.12006. PMID 23488788.
- ^ https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/arecaidine