Guvacine

Guvacine
Names
	IUPAC name 1,2,3,6-Tetrahydropyridine-5-carboxylic acid
Identifiers
CAS Number	498-96-4;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL76768;
ChemSpider	3412;
IUPHAR/BPS	4691;
KEGG	C10149;
PubChem CID	3532;
UNII	41538P325K ;
	InChI InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) Key: QTDZOWFRBNTPQR-UHFFFAOYSA-N; InChI=1/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) Key: QTDZOWFRBNTPQR-UHFFFAOYAX;
	SMILES C1CNCC(=C1)C(=O)O;
Properties
Chemical formula	C6H9NO2
Molar mass	127.143 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Guvacine is an alkaloid in areca nuts.^[1]It is the N-demethylated derivative of arecaidine, which is found in areca nuts as well.It is GABA uptake inhibitor.^[2]

References

^ Voigt, V; Laug, L; Zebisch, K; Thondorf, I; Markwardt, F; Brandsch, M (2013). "Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1)". The Journal of Pharmacy and Pharmacology. 65 (4): 582–90. doi:10.1111/jphp.12006. PMID 23488788.
^ https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/arecaidine