CI-966

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CI-966
CI 966.svg
Names
Other names
1-[2-[bis[4-(Trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine-3-carboxylic acid
Identifiers
110283-66-4
ChemSpider 171978
4612
Jmol-3D images Image
PubChem 198693
Properties
C23H21F6NO3
Molar mass 509.87
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

CI-966 is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1.

References[edit]

External links[edit]

  • Borden LA, Murali Dhar TG, Smith KE, Weinshank RL, Branchek TA, Gluchowski C (October 1994). "Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1". European Journal of Pharmacology 269 (2): 219–24. doi:10.1016/0922-4106(94)90089-2. PMID 7851497. 
  • Phillis JW (September 1995). "CI-966, a GABA uptake inhibitor, antagonizes ischemia-induced neuronal degeneration in the gerbil". General Pharmacology 26 (5): 1061–4. doi:10.1016/0306-3623(94)00270-W. PMID 7557251.