18-Deoxyaldosterone
Appearance
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Clinical data | |
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Other names | 11β,18-epoxy-21-hydroxypregn-4-ene-3,20-dione |
Drug class | Antimineralocorticoid |
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PubChem CID | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C21H28O4 |
Molar mass | 344.451 g·mol−1 |
3D model (JSmol) | |
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18-Deoxyaldosterone is a steroidal antimineralocorticoid with mixed agonist–antagonist but predominantly antagonistic activity at the mineralocorticoid receptor.[1]
References
- ^ Duax, William L.; Griffin, Jane F.; Strong, Phyllis D.; Funder, John W.; Ulick, Stanley (1982). "Molecular structure of 18-deoxyaldosterone and its relationship to receptor binding and activity". Journal of the American Chemical Society. 104 (25): 7291–7293. doi:10.1021/ja00389a063. ISSN 0002-7863.