From Wikipedia, the free encyclopedia
Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene .[ 5] [ 6]
Membrane-associated p40, in together with RAB9A , facilitates the transport of the mannose 6-phosphate receptor (MPR ) from endosomes to the trans-Golgi network .[ 5]
Interactions
RABEPK has been shown to interact with RAB9A [ 5] and FYVE finger-containing phosphoinositide kinase .[ 7]
References
Further reading
Aivazian D, Serrano RL, Pfeffer S (2006). "TIP47 is a key effector for Rab9 localization" . J. Cell Biol . 173 (6): 917–26. doi :10.1083/jcb.200510010 . PMC 2063917 . PMID 16769818 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 . PMID 15164053 .
Gstaiger M, Luke B, Hess D, et al. (2003). "Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI". Science . 302 (5648): 1208–12. Bibcode :2003Sci...302.1208G . doi :10.1126/science.1088401 . PMID 14615539 . S2CID 26836888 .
Ikonomov OC, Sbrissa D, Mlak K, et al. (2004). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40" . J. Biol. Chem . 278 (51): 50863–71. doi :10.1074/jbc.M307260200 . PMID 14530284 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
External links