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Swine acute diarrhea syndrome coronavirus

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Swine acute diarrhea syndrome coronavirus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Nidovirales
Family: Coronaviridae
Genus: Alphacoronavirus
Subgenus: Rhinacovirus
Virus:
Swine acute diarrhea syndrome coronavirus

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a coronavirus related to Rhinolophus bat coronavirus HKU2. It is transmitted through the feces of horseshoe bats to pigs. Piglets less than 5 days old die with a probability of 90%. SADS-CoV was identified during the Severe acute respiratory syndrome outbreak caused by Severe acute respiratory syndrome-related coronavirus in Guangdong 2016 onwards, where it caused the death of more than 24,000 piglets on 4 farms. Current research says that it can infect humans.[1]

Detection

The SADS-CoV in the pigs was found to be 98.48% genetically identical to one collected in anal swabs from 2013–2016 of the Chinese rufous horseshoe bat (Rhinolophus sinicus), Least horseshoe bat (Rhinolopus pusillus), king horseshoe bat (Rhinolopus rex), intermediate horseshoe bat (Rhinolopus affinus).[2]

References

  1. ^ "Swine coronavirus replicates in human cells: Scientists reveal potential of swine coronavirus jumping from animals to people". ScienceDaily. Retrieved 2020-10-15., which references: Edwards, Caitlin E.; Yount, Boyd L.; Graham, Rachel L.; Leist, Sarah R.; Hou, Yixuan J.; Dinnon, Kenneth H.; Sims, Amy C.; Swanstrom, Jesica; Gully, Kendra; Scobey, Trevor D.; Cooley, Michelle R. (2020-10-07). "Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection". Proceedings of the National Academy of Sciences. doi:10.1073/pnas.2001046117. ISSN 0027-8424. PMID 33046644.
  2. ^ Zhou, Peng; Fan, Hang; Lan, Tian; Yang, Xing-Lou; Shi, Wei-Feng; Zhang, Wei; Zhu, Yan; Zhang, Ya-Wei; Xie, Qing-Mei; Mani, Shailendra; Zheng, Xiao-Shuang; Li, Bei; Li, Jin-Man; Guo, Hua; Pei, Guang-Qian; An, Xiao-Ping; Chen, Jun-Wei; Zhou, Ling; Mai, Kai-Jie; Wu, Zi-Xian; Li, Di; Anderson, Danielle E.; Zhang, Li-Biao; Li, Shi-Yue; Mi, Zhi-Qiang; He, Tong-Tong; Cong, Feng; Guo, Peng-Ju; Huang, Ren; et al. (2018). "Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin". Nature. 556 (7700): 255–258. Bibcode:2018Natur.556..255Z. doi:10.1038/s41586-018-0010-9. PMID 29618817.
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