Afamin

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AFM
Identifiers
AliasesAFM, ALB2, ALBA, ALF, afamin
External IDsMGI: 2429409 HomoloGene: 881 GeneCards: AFM
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for AFM
Genomic location for AFM
Band4q13.3Start73,481,683 bp[1]
End73,504,001 bp[1]
RNA expression pattern
PBB GE AFM 206840 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001133

NM_145146

RefSeq (protein)

NP_001124

NP_660128

Location (UCSC)Chr 4: 73.48 – 73.5 MbChr 5: 90.52 – 90.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Afamin is a protein that in humans is encoded by the AFM gene.[5][6]

Function[edit]

This gene is a member of the albumin gene family, which comprises four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000079557 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029369 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, Trollinger DB, Mayer JP, Wright SD, Zukowski MM (Aug 1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J Biol Chem. 269 (27): 18149–54. PMID 7517938.
  6. ^ a b "Entrez Gene: AFM afamin".

External links[edit]

Further reading[edit]