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Afamin

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(Redirected from AFM (gene))
AFM
Identifiers
AliasesAFM, ALB2, ALBA, ALF, afamin
External IDsOMIM: 104145; MGI: 2429409; HomoloGene: 881; GeneCards: AFM; OMA:AFM - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001133

NM_145146

RefSeq (protein)

NP_001124

NP_660128

Location (UCSC)Chr 4: 73.48 – 73.5 MbChr 5: 90.67 – 90.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Afamin is a protein that in humans is encoded by the AFM gene.[5][6]

Function

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This gene is a member of the albumin gene family, which comprises four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000079557Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029369Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lichenstein HS, Lyons DE, Wurfel MM, Johnson DA, McGinley MD, Leidli JC, Trollinger DB, Mayer JP, Wright SD, Zukowski MM (Aug 1994). "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family". J Biol Chem. 269 (27): 18149–54. doi:10.1016/S0021-9258(17)32429-8. PMID 7517938.
  6. ^ a b "Entrez Gene: AFM afamin".
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Further reading

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