AP1G2

AP1G2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2E9G, 2YMT, 3ZHF, 4BCX
Identifiers
Aliases	AP1G2, G2AD, adaptor related protein complex 1 gamma 2 subunit, adaptor related protein complex 1 subunit gamma 2
External IDs	OMIM: 603534; MGI: 1328307; HomoloGene: 49141; GeneCards: AP1G2; OMA:AP1G2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,568,070 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,344,050 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; granulocyte; ; anterior pituitary; ; right uterine tube; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; right frontal lobe; ; left ovary; ; right ovary; ; mucosa of transverse colon;
	Top expressed in
	duodenum; ; yolk sac; ; granulocyte; ; jejunum; ; otic vesicle; ; lip; ; ileum; ; crypt of lieberkuhn of small intestine; ; otic placode; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi-associated vesicle; membrane coat; Golgi membrane; endosome; Golgi apparatus; endosome membrane; transport vesicle; membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle; clathrin adaptor complex; AP-1 adaptor complex;
Biological process	protein transport; intracellular protein transport; viral process; vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	8906
	11766
	ENSG00000213983
	ENSMUSG00000040701
	O75843
	O88512
NM_001282474; NM_001282475; NM_003917; NM_080545; NM_001354673;
	NM_001354674; NM_001354675; NM_001354677; NM_001354681
	NM_007455; NM_001303502
NP_001269403; NP_001269404; NP_003908; NP_001341602; NP_001341603;
	NP_001341604; NP_001341606; NP_001341610
	NP_001290431; NP_031481
	Wikidata
View/Edit Human	View/Edit Mouse

AP-1 complex subunit gamma-like 2 is a protein that in humans is encoded by the AP1G2 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

AP1G2 has been shown to interact with NEDD4.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000213983 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040701 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Takatsu H, Sakurai M, Shin HW, Murakami K, Nakayama K (Oct 1998). "Identification and characterization of novel clathrin adaptor-related proteins". J Biol Chem. 273 (38): 24693–700. doi:10.1074/jbc.273.38.24693. PMID 9733768.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Lewin DA, Sheff D, Ooi CE, Whitney JA, Yamamoto E, Chicione LM, Webster P, Bonifacino JS, Mellman I (Oct 1998). "Cloning, expression, and localization of a novel gamma-adaptin-like molecule". FEBS Lett. 435 (2–3): 263–8. doi:10.1016/S0014-5793(98)01083-7. PMID 9762922.
^ "Entrez Gene: AP1G2 adaptor-related protein complex 1, gamma 2 subunit".
^ Rost, Martina; Döring Tatjana; Prange Reinhild (Nov 2008). "gamma2-Adaptin, a ubiquitin-interacting adaptor, is a substrate to coupled ubiquitination by the ubiquitin ligase Nedd4 and functions in the endosomal pathway". J. Biol. Chem. 283 (46). United States: 32119–30. doi:10.1074/jbc.M802632200. ISSN 0021-9258. PMID 18772139. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading