AP1G2

AP1G2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2E9G, 2YMT, 3ZHF, 4BCX
Identifiers
Aliases	AP1G2, G2AD, adaptor related protein complex 1 gamma 2 subunit, adaptor related protein complex 1 subunit gamma 2
External IDs	OMIM: 603534 MGI: 1328307 HomoloGene: 49141 GeneCards: AP1G2
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,568,070 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,344,050 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right uterine tube; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; minor salivary glands; ; body of pancreas; ; skin of abdomen; ; spleen; ; putamen; ; nucleus accumbens;
	Top expressed in
	duodenum; ; yolk sac; ; jejunum; ; lip; ; ileum; ; crypt of lieberkuhn of small intestine; ; otic placode; ; thymus; ; esophagus; ; Paneth cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	Golgi-associated vesicle; membrane coat; Golgi membrane; endosome; Golgi apparatus; endosome membrane; transport vesicle; membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle; clathrin adaptor complex; AP-1 adaptor complex;
Biological process	protein transport; intracellular protein transport; viral process; vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	8906
	11766
	ENSG00000213983
	ENSMUSG00000040701
	O75843
	O88512
NM_001282474; NM_001282475; NM_003917; NM_080545; NM_001354673;
	NM_001354674; NM_001354675; NM_001354677; NM_001354681
	NM_007455; NM_001303502
NP_001269403; NP_001269404; NP_003908; NP_001341602; NP_001341603;
	NP_001341604; NP_001341606; NP_001341610
	NP_001290431; NP_031481
	Wikidata
View/Edit Human	View/Edit Mouse

AP-1 complex subunit gamma-like 2 is a protein that in humans is encoded by the AP1G2 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

AP1G2 has been shown to interact with NEDD4.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000213983 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040701 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Takatsu H, Sakurai M, Shin HW, Murakami K, Nakayama K (Oct 1998). "Identification and characterization of novel clathrin adaptor-related proteins". J Biol Chem. 273 (38): 24693–700. doi:10.1074/jbc.273.38.24693. PMID 9733768.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Lewin DA, Sheff D, Ooi CE, Whitney JA, Yamamoto E, Chicione LM, Webster P, Bonifacino JS, Mellman I (Oct 1998). "Cloning, expression, and localization of a novel gamma-adaptin-like molecule". FEBS Lett. 435 (2–3): 263–8. doi:10.1016/S0014-5793(98)01083-7. PMID 9762922.
^ "Entrez Gene: AP1G2 adaptor-related protein complex 1, gamma 2 subunit".
^ Rost, Martina; Döring Tatjana; Prange Reinhild (Nov 2008). "gamma2-Adaptin, a ubiquitin-interacting adaptor, is a substrate to coupled ubiquitination by the ubiquitin ligase Nedd4 and functions in the endosomal pathway". J. Biol. Chem. 283 (46). United States: 32119–30. doi:10.1074/jbc.M802632200. ISSN 0021-9258. PMID 18772139. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

Interactions

References

Further reading