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Protein-coding gene in the species Homo sapiens
ATP synthase subunit g, mitochondrial is an enzyme that in humans is encoded by the ATP5MG gene .[ 5] [ 6] [ 7]
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the g subunit of the F0 complex.[ 7]
The function of subunit G is currently unknown. There is no counterpart in chloroplast or bacterial F-ATPases identified so far.[ 8]
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