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All-trans-decaprenyl-diphosphate synthase

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All-trans-decaprenyl-diphosphate synthase
Identifiers
EC no.2.5.1.91
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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All-trans-decaprenyl-diphosphate synthase (EC 2.5.1.91, decaprenyl-diphosphate synthase, decaprenyl pyrophosphate synthetase, polyprenylpyrophosphate synthetase, terpenoidallyltransferase, terpenyl pyrophosphate synthetase, trans-prenyltransferase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate 7 diphosphate + all-trans-decaprenyl diphosphate

This enzyme catalyses the condensation reactions resulting in the formation of all-trans-decaprenyl diphosphate.

References

  1. ^ Saiki, R.; Nagata, A.; Kainou, T.; Matsuda, H.; Kawamukai, M. (2005). "Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans". FEBS J. 272 (21): 5606–5622. doi:10.1111/j.1742-4658.2005.04956.x. PMID 16262699.