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Protein-coding gene in the species Homo sapiens
BTB/POZ domain-containing protein 1 is a protein that in humans is encoded by the BTBD1 gene .[ 5]
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.[ 5]
BTBD1 has been shown to interact with TOP1 .[ 6]
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