CADPS

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CADPS
Protein CADPS PDB 1wi1.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CADPS, CADPS1, CAPS, CAPS1, UNC-31, Ca2+ dependent secretion activator, calcium dependent secretion activator
External IDs MGI: 1350922 HomoloGene: 2755 GeneCards: CADPS
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003716
NM_183393
NM_183394

NM_001042617
NM_012061

RefSeq (protein)

NP_003707
NP_899630
NP_899631

NP_001036082.1
NP_036191.2
NP_001036082
NP_036191

Location (UCSC) Chr 3: 62.4 – 62.88 Mb Chr 14: 12.37 – 12.82 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.[3][4]

CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. CADPS acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Walent JH, Porter BW, Martin TF (Oct 1992). "A novel 145 kd brain cytosolic protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine cells". Cell. 70 (5): 765–75. doi:10.1016/0092-8674(92)90310-9. PMID 1516133. 
  4. ^ a b "Entrez Gene: CADPS Ca2+-dependent secretion activator". 

External links[edit]

Further reading[edit]