CALML5

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CALML5
Protein CALML5 PDB 2b1u.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CALML5, CLSP, calmodulin like 5
External IDs MGI: 1931464 HomoloGene: 49485 GeneCards: CALML5
RNA expression pattern
PBB GE CALML5 220414 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017422

NM_020036

RefSeq (protein)

NP_059118

NP_064420.2
NP_064420

Location (UCSC) Chr 10: 5.5 – 5.5 Mb Chr 13: 3.84 – 3.84 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.[3][4]

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Mehul B, Bernard D, Simonetti L, Bernard MA, Schmidt R (Jun 2000). "Identification and cloning of a new calmodulin-like protein from human epidermis". J Biol Chem. 275 (17): 12841–7. doi:10.1074/jbc.275.17.12841. PMID 10777582. 
  4. ^ a b "Entrez Gene: CALML5 calmodulin-like 5". 

External links[edit]

Further reading[edit]