CAP1

CAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1K8F
Identifiers
Aliases	CAP1, CAP, CAP1-PEN, CAP, adenylate cyclase-associated protein 1 (yeast), adenylate cyclase associated protein 1
External IDs	OMIM: 617801; MGI: 88262; HomoloGene: 74572; GeneCards: CAP1; OMA:CAP1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	122,779,849 bp
RNA expression pattern
	n/a
	Top expressed in
	granulocyte; ; lateral septal nucleus; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; transitional epithelium of urinary bladder; ; tibiofemoral joint; ; cervix; ; yolk sac; ; decidua; ; lip;
	; ;
	More reference expression data
Gene ontology
Molecular function	adenylate cyclase binding; actin binding;
Cellular component	cytoplasm; plasma membrane; extracellular exosome; membrane; focal adhesion; cortical actin cytoskeleton; extracellular region; extracellular space; azurophil granule lumen;
Biological process	establishment or maintenance of cell polarity; ameboidal-type cell migration; receptor-mediated endocytosis; actin cytoskeleton organization; cytoskeleton organization; signal transduction; activation of adenylate cyclase activity; cell morphogenesis; actin polymerization or depolymerization; neutrophil degranulation; regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Orthologs
	10487
	12331
	ENSG00000131236
	ENSMUSG00000028656
	Q01518; Q5T0R9
	P40124
	NM_001105530; NM_006367; NM_001330502
	NM_001301067; NM_007598; NM_001358035; NM_001358036
NP_001099000; NP_001317431; NP_006358; NP_001337404; NP_001337405;
	NP_001337406; NP_001337407; NP_001337408; NP_001337409; NP_001337410; NP_001337411; NP_001337412; NP_001337413; NP_001337414
	NP_001287996; NP_031624; NP_001344964; NP_001344965
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene.^[4]^[5]^[6]

Template:PBB Summary

Interactions

CAP1 has been shown to interact with ACTG1^[7] and CAP2.^[5]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028656 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matviw H, Yu G, Young D (Nov 1992). "Identification of a human cDNA encoding a protein that is structurally and functionally related to the yeast adenylyl cyclase-associated CAP proteins". Mol Cell Biol. 12 (11): 5033–40. PMC 360436. PMID 1406678.
^ ^a ^b Hubberstey A, Yu G, Loewith R, Lakusta C, Young D (Apr 1997). "Mammalian CAP interacts with CAP, CAP2, and actin". J Cell Biochem. 61 (3): 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. PMID 8761950.
^ "Entrez Gene: CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)".
^ Hubberstey, A; Yu G; Loewith R; Lakusta C; Young D (Jun 1996). "Mammalian CAP interacts with CAP, CAP2, and actin". J. Cell. Biochem. 61 (3). UNITED STATES: 459–66. doi:10.1002/(SICI)1097-4644(19960601)61:3<459::AID-JCB13>3.0.CO;2-E. ISSN 0730-2312. PMID 8761950. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading