CDC40

CDC40
Identifiers
Aliases	CDC40, EHB3, PRP17, PRPF17, cell division cycle 40, PCH15
External IDs	OMIM: 605585; MGI: 1918963; HomoloGene: 5716; GeneCards: CDC40; OMA:CDC40 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	110,254,275 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	40,759,307 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; sperm; ; mononuclear cell; ; Achilles tendon; ; monocyte; ; secondary oocyte; ; skin of hip; ; mucosa of ileum; ; bone marrow; ; skin of thigh;
	Top expressed in
	hand; ; lumbar subsegment of spinal cord; ; Rostral migratory stream; ; genital tubercle; ; otolith organ; ; utricle; ; zygote; ; interventricular septum; ; tail of embryo; ; Paneth cell;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	catalytic step 2 spliceosome; spliceosomal complex; nucleoplasm; nucleus; U2-type catalytic step 2 spliceosome; nuclear speck;
Biological process	mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; mRNA processing; mRNA export from nucleus; mRNA 3'-end processing; RNA splicing; RNA export from nucleus;
	Sources:Amigo / QuickGO
Orthologs
	51362
	71713
	ENSG00000168438
	ENSMUSG00000038446
	O60508
	Q9DC48
	NM_015891
	NM_027879
	NP_056975
	NP_082155
	Wikidata
View/Edit Human	View/Edit Mouse

Pre-mRNA-processing factor 17 is a protein that in humans is encoded by the CDC40 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168438 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038446 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ben Yehuda S, Dix I, Russell CS, Levy S, Beggs JD, Kupiec M (Oct 1998). "Identification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle control". RNA. 4 (10): 1304–12. doi:10.1017/S1355838298980712. PMC 1369702. PMID 9769104.
^ Lindsey LA, Garcia-Blanco MA (Jan 1999). "Functional conservation of the human homolog of the yeast pre-mRNA splicing factor Prp17p". J Biol Chem. 273 (49): 32771–5. doi:10.1074/jbc.273.49.32771. PMID 9830021.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: CDC40 cell division cycle 40 homolog (S. cerevisiae)".