CLEC12A

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CLEC12A
Identifiers
Aliases CLEC12A, CLL-1, CLL1, DCAL-2, MICL, CD371, C-type lectin domain family 12 member A
External IDs MGI: 3040968 HomoloGene: 51378 GeneCards: CLEC12A
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001207010
NM_001300730
NM_138337
NM_201623
NM_201625

NM_177686

RefSeq (protein)

NP_001193939
NP_001287659
NP_612210
NP_963917

NP_808354.1
NP_808354

Location (UCSC) Chr 12: 9.95 – 10 Mb Chr 6: 129.34 – 129.37 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

C-type lectin domain family 12 member A is a protein that in humans is encoded by the CLEC12A gene.[3]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.[3]

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