CLEC4A

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CLEC4A
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CLEC4A, CLECSF6, DCIR, DDB27, LLIR, CD367, HDCGC13P, C-type lectin domain family 4 member A
External IDs MGI: 1349412 HomoloGene: 49291 GeneCards: CLEC4A
RNA expression pattern
PBB GE CLEC4A 219947 at fs.png

PBB GE CLEC4A 221724 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016184
NM_194447
NM_194448
NM_194450

NM_001170332
NM_001170333
NM_011999

RefSeq (protein)

NP_057268
NP_919429
NP_919430
NP_919432

Location (UCSC) Chr 12: 8.12 – 8.14 Mb Chr 6: 123.11 – 123.14 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.[3][4]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bates EE, Fournier N, Garcia E, Valladeau J, Durand I, Pin JJ, Zurawski SM, Patel S, Abrams JS, Lebecque S, Garrone P, Saeland S (Sep 1999). "APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif". J Immunol. 163 (4): 1973–83. PMID 10438934. 
  4. ^ a b "Entrez Gene: CLEC4A C-type lectin domain family 4, member A". 

External links[edit]

Further reading[edit]