COG5

COG5
Identifiers
Aliases	COG5, CDG2I, GOLTC1, GTC90, component of oligomeric golgi complex 5
External IDs	OMIM: 606821; MGI: 2145130; HomoloGene: 42221; GeneCards: COG5; OMA:COG5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,564,514 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	31,987,629 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; Achilles tendon; ; bone marrow cells; ; sural nerve; ; tonsil; ; epithelium of colon; ; skeletal muscle tissue; ; endometrium; ; smooth muscle tissue; ; right auricle;
	Top expressed in
	genital tubercle; ; tail of embryo; ; spermatocyte; ; ciliary body; ; spermatid; ; right ventricle; ; dentate gyrus of hippocampal formation granule cell; ; thymus; ; neural layer of retina; ; carotid body;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	cytoplasm; Golgi transport complex; Golgi membrane; cytosol; Golgi apparatus; membrane; nucleoplasm; trans-Golgi network membrane;
Biological process	protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport; intra-Golgi vesicle-mediated transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	10466
	238123
	ENSG00000164597; ENSG00000284369
	ENSMUSG00000035933
	Q9UP83
	Q8C0L8
	NM_001161520; NM_006348; NM_181733
	NM_001163126
NP_001154992; NP_006339; NP_859422; NP_001366440; NP_001366441;
	NP_001366442; NP_001366443; NP_001366444; NP_001366445
	NP_001156598
	Wikidata
View/Edit Human	View/Edit Mouse

Conserved oligomeric Golgi complex subunit 5 is a protein that in humans is encoded by the COG5 gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

COG5 has been shown to interact with COG7^[8] and COG4.^[8]

References

^ ^a ^b ^c ENSG00000284369 GRCh38: Ensembl release 89: ENSG00000164597, ENSG00000284369 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035933 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Walter DM, Paul KS, Waters MG (Dec 1998). "Purification and characterization of a novel 13 S hetero-oligomeric protein complex that stimulates in vitro Golgi transport". J Biol Chem. 273 (45): 29565–76. doi:10.1074/jbc.273.45.29565. PMID 9792665.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297. PMID 11980916.
^ "Entrez Gene: COG5 component of oligomeric golgi complex 5".
^ ^a ^b Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. 279 (23). United States: 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

External links

GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview

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This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] ENSG00000284369 GRCh38: Ensembl release 89: ENSG00000164597, ENSG00000284369 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035933 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9792665-5] Walter DM, Paul KS, Waters MG (Dec 1998). "Purification and characterization of a novel 13 S hetero-oligomeric protein complex that stimulates in vitro Golgi transport". J Biol Chem. 273 (45): 29565–76. doi:10.1074/jbc.273.45.29565. PMID 9792665.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[pmid11980916-6] Ungar D, Oka T, Brittle EE, Vasile E, Lupashin VV, Chatterton JE, Heuser JE, Krieger M, Waters MG (Apr 2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function". J Cell Biol. 157 (3): 405–15. doi:10.1083/jcb.200202016. PMC 2173297. PMID 11980916.

[entrez-7] "Entrez Gene: COG5 component of oligomeric golgi complex 5".

[pmid15047703-8] Loh, Eva; Hong Wanjin (Jun 2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex". J. Biol. Chem. 279 (23). United States: 24640–8. doi:10.1074/jbc.M400662200. ISSN 0021-9258. PMID 15047703. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)

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Interactions

References

Further reading

External links