CPN1

CPN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2NSM
Identifiers
Aliases	CPN1, CPN, SCPN, carboxypeptidase N subunit 1
External IDs	OMIM: 603103; MGI: 2135874; HomoloGene: 1002; GeneCards: CPN1; OMA:CPN1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	100,081,869 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	43,974,995 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; gonad; ; testicle; ; buccal mucosa cell; ; mucosa of ileum; ; skin of thigh; ; right testis; ; left testis; ; kidney; ; human kidney;
	Top expressed in
	left lobe of liver; ; yolk sac; ; islet of Langerhans; ; epithelium of stomach; ; blastocyst; ; right kidney; ; pyloric antrum; ; proximal tubule; ; morula; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	carboxypeptidase activity; peptidase activity; zinc ion binding; hydrolase activity; metallopeptidase activity; metal ion binding; metallocarboxypeptidase activity; serine-type carboxypeptidase activity;
Cellular component	extracellular space; Golgi apparatus; secretory granule; soma; synaptic membrane; extracellular region;
Biological process	response to glucocorticoid; bradykinin catabolic process; proteolysis; insulin processing; regulation of complement activation; peptide metabolic process; protein processing;
	Sources:Amigo / QuickGO
Orthologs
	1369
	93721
	ENSG00000120054
	ENSMUSG00000025196
	P15169
	Q9JJN5
	NM_001308
	NM_030703
	NP_001299
	NP_109628
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120054 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025196 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Riley DA, Tan F, Miletich DJ, Skidgel RA (Apr 1999). "Chromosomal localization of the genes for human carboxypeptidase D (CPD) and the active 50-kilodalton subunit of human carboxypeptidase N (CPN1)". Genomics. 50 (1): 105–8. doi:10.1006/geno.1998.5295. PMID 9628828.
^ Gebhard W, Schube M, Eulitz M (Mar 1989). "cDNA cloning and complete primary structure of the small, active subunit of human carboxypeptidase N (kininase 1)". Eur J Biochem. 178 (3): 603–7. doi:10.1111/j.1432-1033.1989.tb14488.x. PMID 2912725.
^ "Entrez Gene: CPN1 carboxypeptidase N, polypeptide 1".

References

Further reading