CPN2

CPN2
Identifiers
Aliases	CPN2, ACBP, carboxypeptidase N subunit 2
External IDs	OMIM: 603104; MGI: 1919006; HomoloGene: 19487; GeneCards: CPN2; OMA:CPN2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	194,351,328 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	30,086,317 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; human kidney; ; testicle; ; kidney tubule; ; right adrenal gland; ; right adrenal cortex; ; glomerulus; ; metanephric glomerulus; ; left adrenal gland; ; left adrenal cortex;
	Top expressed in
	left lobe of liver; ; brown adipose tissue; ; sexually immature organism; ; yolk sac; ; aorta; ; duodenum; ; ascending aorta; ; jejunum; ; precursor cell; ; human fetus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme regulator activity; metallocarboxypeptidase activity;
Cellular component	blood microparticle; extracellular exosome; extracellular region; extracellular space; extracellular matrix;
Biological process	protein stabilization; regulation of catalytic activity; proteolysis; regulation of complement activation;
	Sources:Amigo / QuickGO
Orthologs
	1370
	71756
	ENSG00000178772
	ENSMUSG00000023176
	P22792
	Q9DBB9
	NM_001080513; NM_001291988; NM_001309
	NM_027904
	NP_001073982; NP_001278917
	NP_082180
	Wikidata
View/Edit Human	View/Edit Mouse

Carboxypeptidase N subunit 2 is an enzyme that in humans is encoded by the CPN2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000178772 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023176 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tan F, Weerasinghe DK, Skidgel RA, Tamei H, Kaul RK, Roninson IB, Schilling JW, Erdos EG (Feb 1990). "The deduced protein sequence of the human carboxypeptidase N high molecular weight subunit reveals the presence of leucine-rich tandem repeats". J Biol Chem. 265 (1): 13–9. PMID 2378615.
^ Riley DA, Tan F, Miletich DJ, Skidgel RA (Apr 1999). "Chromosomal localization of the genes for human carboxypeptidase D (CPD) and the active 50-kilodalton subunit of human carboxypeptidase N (CPN1)". Genomics. 50 (1): 105–8. doi:10.1006/geno.1998.5295. PMID 9628828.
^ "Entrez Gene: CPN2 carboxypeptidase N, polypeptide 2".

Human CPN2 genome location and CPN2 gene details page in the UCSC Genome Browser.