CRISP1

CRISP1
Identifiers
Aliases	CRISP1, AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP, HEL-S-57, cysteine rich secretory protein 1
External IDs	OMIM: 601193; MGI: 1925331; HomoloGene: 81683; GeneCards: CRISP1; OMA:CRISP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	49,877,096 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	18,216,126 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; tail of epididymis; ; sperm; ; seminal vesicula; ; caput epididymis; ; left testis; ; right testis; ; buccal mucosa cell; ; endometrium; ; head;
	Top expressed in
	spermatid; ; white adipose tissue; ; dorsal striatum; ; nucleus of brain; ; male reproductive system; ; telencephalic nucleus; ; testicle; ; hypothalamus; ; brain stem; ; midbrain tegmentum;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium channel regulator activity;
Cellular component	extracellular region; nucleus; extracellular space;
Biological process	fusion of sperm to egg plasma membrane involved in single fertilization; regulation of acrosome reaction; binding of sperm to zona pellucida; regulation of molecular function;
	Sources:Amigo / QuickGO
Orthologs
	167
	78081
	ENSG00000124812
	ENSMUSG00000025774
	P54107
	n/a
	NM_001131; NM_001205220; NM_170609
	NM_030033; NM_001347047; NM_001347048
	NP_001122; NP_001192149; NP_733758
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Cysteine-rich secretory protein 1 is a cysteine-rich secretory protein that in humans is encoded by the CRISP1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124812 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025774 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hayashi M, Fujimoto S, Takano H, Ushiki T, Abe K, Ishikura H, Yoshida MC, Kirchhoff C, Ishibashi T, Kasahara M (Feb 1997). "Characterization of a human glycoprotein with a potential role in sperm-egg fusion: cDNA cloning, immunohistochemical localization, and chromosomal assignment of the gene (AEGL1)". Genomics. 32 (3): 367–74. doi:10.1006/geno.1996.0131. PMID 8838800.
^ "Entrez Gene: CRISP1 cysteine-rich secretory protein 1".