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Carbonic anhydrase II

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Carbonic anhydrase II (gene name CA2), is one of fourteen forms of human α carbonic anhydrases. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule. [1]

Interactions

Carbonic anhydrase II has been shown to interact with Band 3[2][3][4][5] and Sodium-hydrogen antiporter 1.[6]

References

  1. ^ "Entrez Gene: CA2 carbonic anhydrase II".
  2. ^ Sterling, D; Reithmeier R A; Casey J R (December 2001). "A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers". J. Biol. Chem. 276 (51). United States: 47886–94. doi:10.1074/jbc.M105959200. ISSN 0021-9258. PMID 11606574. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)CS1 maint: unflagged free DOI (link)
  3. ^ Vince, J W; Reithmeier R A (October 1998). "Carbonic anhydrase II binds to the carboxyl terminus of human band 3, the erythrocyte C1-/HCO3- exchanger". J. Biol. Chem. 273 (43). UNITED STATES: 28430–7. doi:10.1074/jbc.273.43.28430. ISSN 0021-9258. PMID 9774471. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)CS1 maint: unflagged free DOI (link)
  4. ^ Vince, J W; Carlsson U; Reithmeier R A (November 2000). "Localization of the Cl-/HCO3- anion exchanger binding site to the amino-terminal region of carbonic anhydrase II". Biochemistry. 39 (44). UNITED STATES: 13344–9. doi:10.1021/bi0015111. ISSN 0006-2960. PMID 11063570. {{cite journal}}: Cite has empty unknown parameters: |laysummary=, |laydate=, and |laysource= (help)
  5. ^ Vince, J W; Reithmeier R A (May 2000). "Identification of the carbonic anhydrase II binding site in the Cl(-)/HCO(3)(-) anion exchanger AE1". Biochemistry. 39 (18). UNITED STATES: 5527–33. doi:10.1021/bi992564p. ISSN 0006-2960. PMID 10820026. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysummary=, and |laysource= (help)
  6. ^ Li, Xiuju; Alvarez Bernardo; Casey Joseph R; Reithmeier Reinhart A F; Fliegel Larry (September 2002). "Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger". J. Biol. Chem. 277 (39). United States: 36085–91. doi:10.1074/jbc.M111952200. ISSN 0021-9258. PMID 12138085. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)CS1 maint: unflagged free DOI (link)

Further reading

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