Jump to content

Cellosaurus

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Amb sib (talk | contribs) at 20:48, 2 November 2016 (Added Biosharing.org record). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Cellosaurus
Content
DescriptionCellosaurus: a knowledge resource on cell lines
Data types
captured
Cell lines
OrganismsVertebrate, Insect, Tick
Contact
Research centerSwiss Institute of Bioinformatics
LaboratoryCALIPHO
AuthorsAmos_Bairoch
Access
Data formatFlat file database and OBO
Websiteweb.expasy.org/cellosaurus/
Tools
WebSearch
Miscellaneous
LicenseCreative Commons Attribution-NoDerivs
VersioningYes
Data release
frequency
4 to 6 releases per year
Curation policyYes - manual
Bookmarkable
entities
Yes - individual cell line entries

Cellosaurus is an on-line knowledge resource on cell lines. Its scope includes immortalised cell lines, naturally immortal cell lines (example: embryonic stem cells) and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the species of origin. Other types of information include standardised disease terminology (for cancer or genetic disorder cell lines), the transformant used to immortalise a cell line, transfected or knocked-out genes, web links, publication references and cross-references to more than 50 different databases, cell collections and other relevant resources.

Since many cell lines used in research have been misidentified or contaminated, the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee (ICLAC) [1] tables.

For human cell lines, it provides short tandem repeat (STR) profile information, which is critical to the important process of cell line authentication.

It is developed by Amos Bairoch at the CALIPHO group [2] of the Swiss Institute of Bioinformatics (SIB).

References