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Cholestenol Delta-isomerase

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Cholestenol Δ-isomerase
Identifiers
EC no.5.3.3.5
CAS no.37318-47-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a cholestenol Δ-isomerase (EC 5.3.3.5) is an enzyme that catalyzes the chemical reaction

5alpha-cholest-7-en-3beta-ol 5alpha-cholest-8-en-3beta-ol

Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.

See also

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References

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  • Wilton DC, Rahimtula AD, Akhtar M (August 1969). "The reversibility of the delta8-cholestenol-delta7-cholestenol isomerase reaction in cholesterol biosynthesis". The Biochemical Journal. 114 (1): 71–73. doi:10.1042/bj1140071. PMC 1184797. PMID 5810070.