DDX41

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DDX41
Protein DDX41 PDB 2p6n.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DDX41, ABS, MPLPF, DEAD-box helicase 41
External IDs MGI: 1920185 HomoloGene: 9431 GeneCards: DDX41
RNA expression pattern
PBB GE DDX41 217840 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016222
NM_001321732
NM_001321830

NM_134059

RefSeq (protein)

NP_001308661
NP_001308759
NP_057306

NP_598820.2
NP_598820

Location (UCSC) Chr 5: 177.51 – 177.52 Mb Chr 13: 55.53 – 55.54 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Probable ATP-dependent RNA helicase DDX41 is an enzyme that in humans is encoded by the DDX41 gene.[3][4]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Irion U, Leptin M (Feb 2000). "Developmental and cell biological functions of the Drosophila DEAD-box protein abstrakt". Curr Biol. 9 (23): 1373–81. doi:10.1016/S0960-9822(00)80082-2. PMID 10607561. 
  4. ^ a b "Entrez Gene: DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41". 

Further reading[edit]