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Available structures
PDB Ortholog search: PDBe RCSB
Aliases DHRS4, CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2, dehydrogenase/reductase (SDR family) member 4, dehydrogenase/reductase 4
External IDs MGI: 90169 HomoloGene: 49646 GeneCards: DHRS4
Gene location (Human)
Chromosome 14 (human)
Chr. Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for DHRS4
Genomic location for DHRS4
Band 14q11.2 Start 23,953,586 bp[1]
End 23,969,279 bp[1]
RNA expression pattern
PBB GE DHRS4 gnf1h10034 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 14: 23.95 – 23.97 Mb Chr 14: 55.48 – 55.49 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Dehydrogenase/reductase SDR family member 4 is an enzyme that in humans is encoded by the DHRS4 gene.[5][6][7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000157326 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022210 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Fransen M, Van Veldhoven PP, Subramani S (Jul 1999). "Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase". Biochem J. 340 ( Pt 2) (Pt 2): 561–8. PMC 1220285Freely accessible. PMID 10333503. 
  6. ^ Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744Freely accessible. PMID 19027726. 
  7. ^ "Entrez Gene: DHRS4 dehydrogenase/reductase (SDR family) member 4". 

Further reading[edit]