DRG2

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DRG2
Identifiers
Aliases DRG2, developmentally regulated GTP binding protein 2
External IDs MGI: 1342307 HomoloGene: 1061 GeneCards: DRG2
RNA expression pattern
PBB GE DRG2 203267 s at fs.png

PBB GE DRG2 203268 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001388
NM_001330144

NM_021354

RefSeq (protein)

NP_001317073
NP_001379

NP_067329.1
NP_067329

Location (UCSC) Chr 17: 18.09 – 18.11 Mb Chr 11: 60.45 – 60.47 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene.[3][4][5]

The DRG2 gene encodes the developmentally regulated GTP-binding protein 2, a name derived from the fact that it shares significant similarity to known GTP-binding proteins. DRG2 was identified because it is expressed in normal fibroblasts but not in SV40-transformed fibroblasts. Read-through transcripts containing this gene and a downstream gene have been identified, but they are not thought to encode a fusion protein. This gene is located within the Smith-Magenis syndrome region on chromosome 17.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Schenker T, Trueb B (Jun 1998). "Assignment of the gene for a developmentally regulated GTP-binding protein (DRG2) to human chromosome bands 17p13→p12 by in situ hybridization". Cytogenet Cell Genet. 79 (3–4): 274–5. doi:10.1159/000134741. PMID 9605870. 
  4. ^ Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994). "A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts". J Biol Chem. 269 (41): 25447–53. PMID 7929244. 
  5. ^ a b "Entrez Gene: DRG2 developmentally regulated GTP binding protein 2". 

Further reading[edit]