David Callaway

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David J. E. Callaway

David J. E. Callaway is a biological nanophysicist in the New York University School of Medicine, where he is Professor and Laboratory Director. He was trained as a theoretical physicist by Richard Feynman, Kip Thorne, and Cosmas Zachos, and was previously an associate professor at the Rockefeller University after positions at CERN and Los Alamos National Laboratory. Callaway's laboratory discovered potential therapeutics for Alzheimer's disease based upon apomorphine[1] after an earlier paper of his developed models of Alzheimer amyloid formation.[2] He has also initiated the study of protein domain dynamics by neutron spin echo spectroscopy, providing a way to observe protein nanomachines in motion.[3]

Previous work includes the invention of the microcanonical ensemble approach to lattice gauge theory with Aneesur Rahman,[4][5] work on the convexity of the effective potential of quantum field theory,[6] work on Langevin dynamics in quantum field theory with John R. Klauder[7], a monograph on quantum triviality,[8] constraints on the Higgs boson[9] and papers on black holes[10] and superconductors.[11]

Athletic accomplishments[edit]

Everest climbers receive Tengboche blessing. Ginette Harrison, Sir David Hempleman-Adams, David Callaway, Scott McIvor, Lee Nobmann, Brian Blessed.

Dr Callaway is an avid expedition mountaineer and polar explorer.[12] He was a competitor on the first Eco-Challenge.[13]

References[edit]

  1. ^ Lashuel, H. A.; Hartley, D. M.; Balakhaneh, D.; Aggarwal A.; Teichberg S.; Callaway, D. J. E. (2002). "New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease". J Biol Chem. 277 (45): 42881–42890. doi:10.1074/jbc.M206593200. PMID 12167652. 
  2. ^ Tjernberg, L. O.; Callaway, D. J. E.; Tjernberg, A.; Hahne, S.; Lilliehöök, C.; Terenius, L.; Thyberg, J.; Nordstedt, C. (1999). "A molecular model of Alzheimer amyloid ß-peptide fibril formation". J Biol Chem. 274 (18): 12619–12625. doi:10.1074/jbc.274.18.12619. PMID 10212241. 
  3. ^ Bu, Z.; Biehl, R; Monkenbusch, M.; Richter, D.; Callaway, D. J. E. (2005). "Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy". Proc Natl Acad Sci USA. 102 (49): 17646–17651. Bibcode:2005PNAS..10217646B. doi:10.1073/pnas.0503388102. PMC 1345721Freely accessible. PMID 16306270. 
  4. ^ D. J. E. Callaway; A. Rahman (1982). "Microcanonical Ensemble Formulation of Lattice Gauge Theory". Phys. Rev. Lett. 49: 613–616. Bibcode:1982PhRvL..49..613C. doi:10.1103/PhysRevLett.49.613. 
  5. ^ D. J. E. Callaway; A. Rahman (1983). "Lattice gauge theory in the microcanonical ensemble" (PDF). Phys. Rev. D. 28: 1506–1514. Bibcode:1983PhRvD..28.1506C. doi:10.1103/PhysRevD.28.1506. 
  6. ^ D. J. E. Callaway; D. J. Maloof (1982). "Effective potential of lattice φ4 theory". Phys. Rev. D. D27: 406–411. Bibcode:1983PhRvD..27..406C. doi:10.1103/PhysRevD.27.406. 
  7. ^ D. J. E. Callaway; F. Cooper; J. R. Klauder; H. A. Rose (1985). "Langevin simulations in Minkowski space". Nuclear Physics B. 262: 19–32. Bibcode:1985NuPhB.262...19C. doi:10.1016/0550-3213(85)90061-6. 
  8. ^ D. J. E. Callaway (1988). "Triviality Pursuit: Can Elementary Scalar Particles Exist?". Physics Reports. 167: 241–320. Bibcode:1988PhR...167..241C. doi:10.1016/0370-1573(88)90008-7. 
  9. ^ D. J. E. Callaway (1984). "Non-triviality of gauge theories with elementary scalars and upper bounds on Higgs masses". Nuclear Physics B. 233: 189–203. Bibcode:1984NuPhB.233..189C. doi:10.1016/0550-3213(84)90410-3. 
  10. ^ Callaway, D. (1996). "Surface tension, hydrophobicity, and black holes: The entropic connection". Physical Review E. 53 (4): 3738–3744. arXiv:cond-mat/9601111Freely accessible. Bibcode:1996PhRvE..53.3738C. doi:10.1103/PhysRevE.53.3738. PMID 9964684. 
  11. ^ David J. E. Callaway (1990). "On the remarkable structure of the superconducting intermediate state". Nuclear Physics B. 344 (3): 627–645. Bibcode:1990NuPhB.344..627C. doi:10.1016/0550-3213(90)90672-Z. 
  12. ^ Numerous expeditions
  13. ^ Eco-Challenge

External links[edit]